Sr Director, R&D Data Science & Digital Health – Neurodegeneration

At Johnson & Johnson we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated and cured and where treatments are smarter and less invasive and solutions are our expertise in Innovative Medicine and Med Tech.

We are seeking an experienced and visionary Sr Director to lead our data science and digital health strategy for neurodegenerative diseases
. This role will shape and execute innovative approaches leveraging multiomics, digital health technologies, artificial intelligence and clinical/real-world evidence (RWE) to accelerate drug discovery, development and patient impact.

• Define and execute the data science and digital health strategy for neurodegeneration integrating computational biology, AI/ML, digital health and clinical/RWE insights.
• Drive the application of multiomics (genomics, proteomics, transcriptomics, metabolomics, etc.) and integrative analytics to uncover disease mechanisms, biomarkers and novel targets.
• Lead the development, validation and regulatory engagement of digital tools and novel endpoints to enhance clinical trial design, patient monitoring and care pathways.
• Champion the use of machine learning, deep learning, generative and agentic AI to accelerate patient stratification, disease modeling and translational discovery.
• Partner with clinical development and medical affairs to integrate RWE into evidence generation supporting trial optimization, regulatory submissions and real-world impact assessment.
• Build strong cross‑functional and external collaborations with academic groups, technology providers, regulators and consortia to position the company at the forefront of data‑driven neuroscience.
• Recruit, develop and inspire a diverse team of digital health scientists, RWE experts and computational neuroscientists to deliver on strategic initiatives.

• Advanced degree (PhD, MD or equivalent) in neuroscience or quantitative sciences such as biomedical engineering, data science, biostatistics, computational biology or a related field.
• 10 years of relevant industry or academic experience with proven leadership in applying data‑driven methods to drug discovery and development.
• 7 years of experience as a people manager.
• Experience in clinical development is required with demonstrated expertise in neurodegeneration preferred.
• Excellent communication skills with the ability to translate complex data‑driven insights into clear strategies for senior stakeholders and external partners.
• Technical Expertise (2/3):
  1) Proficiency in multiomics integration (e.g. genomics, transcriptomics, proteomics) and advanced statistical/causal inference methods;
  2) Expertise in applying digital health technologies (wearables, sensors, mobile platforms) and novel endpoints in clinical research;
  3) Experience with large‑scale clinical datasets (EHR and real‑world data) and expertise in advanced modeling, longitudinal analysis, and patient stratification.
• Track record of scientific contributions (presentations and publications) in this field is required.
• Familiarity with data standards, privacy regulations and regulatory qualification pathways is required.
• Knowledge of data infrastructures, development of data analysis pipelines and their implementation at scale and state‑of‑the‑art AI methodologies is a plus.
• Competence with programming and analytics environments (e.g. Python, R) with ability to guide technical teams at a strategic level.
• Demonstrated success in leading cross‑disciplinary teams at the interface of data science, biology and clinical development.

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.