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Post Doc - Wolfe Lab

Job in Worcester, Worcester County, Massachusetts, 01609, USA
Listing for: University of Massachusetts Medical School
Full Time position
Listed on 2026-01-12
Job specializations:
  • Research/Development
    Research Scientist, Medical Science
  • Healthcare
    Medical Science
Salary/Wage Range or Industry Benchmark: 61008 - 74088 USD Yearly USD 61008.00 74088.00 YEAR
Job Description & How to Apply Below

Post Doc - Wolfe Lab

Job Number:

Category: Research

Location: Worcester, MA

Shift: Day

Exempt/Non-Exempt: Exempt

Business Unit: UMass Chan Medical School

Department: School - Molecular Cell & Cancer Biology - W495000

Job Type: Full-Time

Union Code: Non Union Position-W63-Residents/Post Docs

Num. Openings: 1

Post Date: Jan. 9, 2026

Work Location: 100% Onsite

Salary Minimum: USD $61,008.00/Hr.

Salary Maximum: USD $74,088.00/Hr.

Job Summary

The Wolfe laboratory will be filling a postdoctoral position to develop therapeutic genome editing reagents for muscular dystrophies and cancer. These projects will focus on:

Responsibilities
  • Development of prime editing reagents with high activity and specificity for the precise correction of common pathogenic mutations associated with Limb Girdle Muscular Dystrophy.
  • Development of genome editing reagents for selective killing of cancer cells harboring gene amplifications.
  • Utilization of unbiased genome-wide techniques for assessing off‑target events and other genomic alterations potentially associated with genome editing.
  • Translation of the developed genome editing reagents to clinical application through in vivo safety and efficacy studies in relevant mouse models.
  • Qualifications

    Candidates should have a Ph.D. in biology, biochemistry, chemistry or a related biomedical science. In addition, the potential candidate must have strong oral and written communication skills and be eager to present research results at national meetings. Prior experience with genome editing systems, cell culture, deep‑sequencing technologies and mouse disease models is advantageous but not required.

    Application Instructions

    Applicants should send a letter (via email) describing their current research activities and their interest in this position, a CV (including publications) and contact information for three references, including your Ph.D. advisor.

    Contact
    • University of Massachusetts Chan Medical School
    • Department of Molecular, Cell and Cancer Biology
    • 364 Plantation Street, LRB Room 619
    • Worcester, MA 01605

    UMass Chan welcomes all qualified applicants and complies with all state and federal anti-discrimination laws.

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