Research Associate - Molecular Medicine & Therapeutics

Overview

Job Title:

Research Associate - Molecular Medicine & Therapeutics

The Chandler Laboratory is seeking a highly motivated and skilled Research Associate to investigate the molecular mechanisms of alternative splicing in cancer, with a particular focus on the p53 tumor suppressor pathway and cell signaling growth pathways. The successful candidate will contribute to cutting-edge research exploring the links between DNA damage, RNA processing, and tumorigenesis, using a combination of cell culture, in vitro splicing assays, and genetically engineered mouse models.

The Research Associate will participate in planning, design, execution, and management of research projects in a foundational (basic) biological/health science research laboratory.

• Investigating the regulation of alternative splicing in response to genotoxic stress, hypoxia and other tumor stressors.
• Characterizing models of splicing regulation and their implications for post-transcriptional regulation.
• Developing and testing therapeutic tools to modulate splicing in cancer-related genes.
• Utilizing novel delivery systems for RNA therapeutics in vivo.

Bachelor’s Level Degree or equivalent combination of education and experience.

Bachelor's Degree or equivalent experience required; 3 years of relevant experience required with Associate's Degree, or 1 year of relevant experience required with Bachelor's Degree. MS degree in a relevant scientific discipline is a plus, experience with RNA processing and splicing assays is highly desirable as is familiarity with animal models (mouse/rat). Ability to translate, adapt and apply academic and/or practical knowledge in the conduct of biological/health science research is required.

Experience in a biological/health science research capacity is preferred.

Function:
Research and Scholarship

Sub Function:
Research

Career Band: S

Career Level:

S1

Location:

Pelotonia Research Center (1040)

Position Type:
Regular

Scheduled

Hours:

40

Shift: First Shift

Final candidates are subject to successful completion of a background check. A drug screen or physical may be required during the post offer process.

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