Oncology Early Stage Clinical Scientist; Director, Non-MD

Oncology Early Stage Clinical Scientist (Director, Non-MD)

• United States - Washingtonantwort – Bothell
• United States - Connecticut - Groton
• United States - Pennsylvania - Collegeville
• United States - New York - New York City

We’re in relentless pursuit of breakthroughs that change patients’ lives. We innovate every day to make the world a થોડ healthier place.

To fully realize Pfizer’s purpose – Breakthroughs that change patients’ lives – we have established a clear set of expectations regarding “what” we need to achieve for patients and “how” we will go about achieving those goals.

Pfizer Research & Development serves as the beating heart of Pfizer's trailblazing product pipeline, the essence of our mission to bring life‑changing medicines to the world.

Pfizer offers competitive compensation and benefits programs designed to meet the diverse needs of our colleagues.

You will lead and coordinate the development of multiple studies of novel biological and small molecules for first in human (FIH), proof of mechanism (POM), early signs of efficacy (ESOE) and proof of concept (POC) studies in Oncology. You will work in close collaboration with the Global Development Lead (GDL) and members of the development team to establish, lead, coordinate, and execute the early oncology clinical development plan(s).

You will lead the development of the clinical protocol and participate as an individual contributor on clinical teams with Pfizer development operations and the project team, to meet enrollment and study delivery timelines. You will also work with other functional disciplines to ensure the full scope and remit of Oncology Early Stage Development (OESD) is represented as needed within clinical study teams (e.g., Research Units, Biostatistics, Clinical Pharmacology, Precision Medicine, and Digital Medicine).

• Partner closely with the Global Development Lead (GDL) in the execution of the clinical development strategy and plan for the assigned molecule(s)/indication(s).
• Responsible for scientific leadership and execution of clinical studies and delivering on innovative clinical study designs, high quality trial execution, safety assessment and interpretation of clinical study results.
• Support execution for all FIH programs through proof-of concept.
• Set the clinical data review strategy, ensure quality data and conduct review of emerging clinical data and trends; review and query CONDITIONS; present and discuss relevant data to appropriate teams, governance bodies, and other internal and external stakeholders.
• Conduct data review, analysis and interpretation of clinical trials data together with the GDL, Clinical Safety, and Biostatistics.
• Serve as technical resource for clinical issues raised by internal and external collaborators, investigators, consultants and contractors.
• Support and assist in the development of publications, abstracts, and presentations.
• May sit on project teams to support clinical development implementation and contribution to key development milestones, e.g., start‑up and delivery of ESoE and PoC trials.
• Participate in project teams to help implement clinical development and contribute to key milestones (e.g., start‑up and delivery of early signs of efficacy [ESoE] and POC trials).
• Lead the preparation of clinical protocols and support other critical documents including clinical development plans, INDs, annual reports, clinical study reports (CSRs), investigator brochures, statistical analysis plans, and regulatory documents.
• Foster a transparent environment that builds strong partnerships and mutual trust among teams and therapeutic areas.
• Coordinate with other clinical research activities within Oncology Research Development (ORD) and the broader Worldwide Research and Development (WRD) organization.
• Develop effective collaborations with key internal and external chứng partners, such as project leaders, research units, biostatistics, regulatory affairs, clinical pharmacology, human genetics, translational oncology, precision medicine, and development operations.
• Partner with Translational Oncology and Biomarker teams to ensure biomarker plans are integrated…