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Director, Cancer Vaccines Technologies

Job in Waltham, Middlesex County, Massachusetts, 02254, USA
Listing for: AstraZeneca
Full Time position
Listed on 2026-01-12
Job specializations:
  • Software Development
    Data Science Manager
Salary/Wage Range or Industry Benchmark: 200000 - 250000 USD Yearly USD 200000.00 250000.00 YEAR
Job Description & How to Apply Below

Are you ready to lead the charge in transforming cancer treatment? As the Director, Cancer Vaccines Technologies in Early Vaccines and Immune Therapies, you will be responsible for leading efforts to develop and deliver a portfolio of new modalities that train the immune system to recognize and eliminate malignant cells. The Director will build on previous experience in cancer vaccines to exploit various vaccine platforms to drive long‑lived, robust immune responses to prevent, treat, and maintain surveillance of tumors.

Building on the current state of the field, the Director will develop preclinical strategy, guide antigen discovery, support vaccine design, and develop combinatorial approaches to amplify clinical impact. The candidate will lead work across cross‑functional teams to build programs, drive collaboration, influence internal stakeholders, and develop a cutting‑edge portfolio of intellectual property. He or she will foster high‑performance and innovation;

build capabilities across immunology, oncology, and translational sciences; and establish clear operating mechanisms to accelerate decision‑making and delivery.

Accountabilities
  • Develop a preclinical pipeline for the design, testing, and delivery of cancer vaccine programs
  • Implement a strategy to explore multiple vaccine modalities to train immunity to eliminate tumors
  • Create an approach to evaluate combinatorial modalities to maximize control, clearance, and surveillance
  • Develop a strategy to drive target discovery and evaluation
  • Work with cross‑disciplinary teams to guide iterative antigen design and preclinical evaluation
  • Establish strategic relationships across the organization and functions
  • Build animal models for rapid evaluation of emerging modalities
  • Support the development of a regulatory strategy to translate programs to clinic
  • Create and foster effective relationships with senior and executive stakeholders in Research, Bioprocess Development, Clinical and Translational Medicine, and Global Project Teams to ensure alignment across functions
  • Pioneer AI‑based strategies to accelerate the pace of innovation at all levels of research
  • Collaborate and guide the evaluation of novel business development opportunities
  • Communicate results internally and externally, as well as their associated risks, uncertainties and limitations
  • Define the training standards for junior colleagues in line with best practices and principles
Essential Skills/Experience
  • PhD or equivalent in immunology, oncology, molecular biology, biochemistry or a related discipline with 10+ years industry experience
  • Proven experience developing novel immunological approaches to deploy immunity to fight tumors
  • Proven experience with immune profiling, tumor modeling, systems biology, and/or immune oncology
  • Experience working in a cross‑functional team to maximize expertise and accelerate success
  • Experience developing and implementing novel methods to support vaccine development
  • Experience supporting or leading interdisciplinary vaccine discovery or development programs
  • Proven experience leading and managing junior colleagues
  • Proven experience developing and controlling budgets
  • Excellent written and verbal communication, business analysis, and consultancy skills
Desirable Skills/Experience
  • PhD or MD degree in immune‑oncology
  • Comfortable working with and leading lab and computational scientists across disciplines
  • Familiarity with animal tumor models
  • Proven track record of publishing relevant results and tools in peer‑reviewed journals, conferences, and other scientific proceedings
  • Experience in life sciences and healthcare
  • Experience in novel methods development and application
  • Experience in a complex global organization
Company Culture

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life‑changing medicines. In‑person working gives us the platform we need to connect, work at pace, and challenge perceptions. That’s why we work, on average, a minimum of three days per week from the office. We balance the expectation of being in the office while respecting individual flexibility.

Join us in our unique and ambitious world.

Company Overview

AstraZeneca is…

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