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Director, US West Medical Science Liaison; MSL Manager

Job in Waltham, Middlesex County, Massachusetts, 02254, USA
Listing for: Zenas BioPharma
Full Time position
Listed on 2026-02-01
Job specializations:
  • Management
    Healthcare Management
  • Healthcare
    Healthcare Management
Salary/Wage Range or Industry Benchmark: 150000 - 200000 USD Yearly USD 150000.00 200000.00 YEAR
Job Description & How to Apply Below
Position: Director, US West Medical Science Liaison (MSL) Manager

Zenas Bio Pharma – Director, US West Medical Science Liaison (MSL) Manager

Zenas is a clinical‑stage global biopharmaceutical company committed to becoming a leader in the development and commercialization of transformative therapies for patients with autoimmune diseases. Our core business strategy combines experienced leadership with a disciplined product candidate acquisition approach to identify, acquire and develop product candidates globally that we believe can provide superior clinical benefits to patients living with autoimmune diseases.

Zenas is advancing two late‑stage, potential franchise molecules, obexelimab and orelabrutinib. Obexelimab is a bifunctional monoclonal antibody designed to bind both CD19 and FcγRIIb to inhibit the activity of cells involved in many autoimmune diseases without depleting them. Orelabrutinib is a potentially best‑in‑class, highly selective CNS‑penetrant, oral, small‑molecule Bruton’s Tyrosine Kinase (BTK) inhibitor with the potential to address compartmentalized inflammation in Multiple Sclerosis.

Earlier‑stage programs include a preclinical IL‑17AA/AF inhibitor and a preclinical brain‑penetrant TYK2 inhibitor.

Position Summary

The US West Medical Science Liaison Manager, Rheumatology, at Zenas is a key Medical Affairs leader responsible for hiring, developing, and managing a high‑performing team of Medical Science Liaisons. This role ensures scientific excellence, compliant external engagement, strategic alignment with medical plans, and the generation of high‑quality insights to advance the company’s therapeutic priorities. The ideal candidate combines strong leadership, deep scientific expertise, and operational discipline to support product launches and lifecycle management.

This position reports to the Executive National Director, Medical Science Liaisons.

Field Team Leadership & Development
  • Manage (recruit, train, coach, and mentor) a team of MSLs to ensure scientific, operational, and compliance excellence.
  • Conduct regular field rides/virtual shadowing to observe skills, provide feedback, and support professional development.
  • Set clear performance expectations and conduct ongoing performance evaluations.
  • Foster a culture of collaboration, accountability, and continuous improvement.
Scientific Strategy & Execution
  • Translate the Medical Affairs strategy into actionable field medical plans.
  • Guide the MSL team on priority scientific topics, key data updates, competitive landscape, and disease state knowledge.
  • Ensure consistent, high‑quality, insights‑driven scientific exchange in alignment with approved materials and compliance standards.
  • Support development and delivery of scientific training for field teams and cross‑functional stakeholders.
Stakeholder Engagement
  • Oversee relationship‑building with key opinion leaders (KOLs), academic investigators, and professional societies.
  • Ensure KOL identification, mapping, and engagement plans are aligned to strategic medical objectives.
  • Partner effectively with Clinical Development, Medical Directors, HEOR, and Commercial (within compliance) to ensure coordinated insights and activities.
Insight Generation & Medical Intelligence
  • Establish processes for capturing, synthesizing, and communicating field insights to Medical Leadership and cross‑functional teams.
  • Identify emerging trends, data gaps, and unmet needs that inform clinical strategy, medical education, and evidence generation plans.
Cross‑Functional Collaboration
  • Ensure appropriate collaboration with Clinical Operations (site support), Safety/Pharmacovigilance, Regulatory, and Commercial teams in alignment with policies.
  • Contribute to advisory boards, congress planning, scientific narrative development, and launch readiness.
  • Partner in the development and execution of scientific resources and medical education initiatives.
Compliance & Operational Excellence
  • Ensure all field medical activities adhere to regulatory, legal, medical, and company policies.
  • Oversee activity reporting, CRM documentation, territory planning, and field metrics.
  • Manage MSL budgets (travel, training, congresses) responsibly and transparently.
  • Support the Medical‑Legal‑Regulatory (MLR) process as needed…
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