Director, Facilities

Madrigal is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a serious liver disease that can progress to cirrhosis, liver failure, need for liver transplantation and premature mortality. Every member of our Madrigal team is connected by our shared purpose: leading the fight against MASH.

Madrigal’s medication, Rezdiffra (resmetirom), is a once‑daily, oral, liver‑directed THR‑β agonist designed to target key underlying causes of MASH. Rezdiffra is the first and only medication approved by both the FDA and European Commission for the treatment of MASH with moderate to advanced fibrosis (F2 to F3). An ongoing Phase 3 outcomes trial is evaluating Rezdiffra for the treatment of compensated MASH cirrhosis (F4c).

Our success is driven by our people. We are building a dynamic, inclusive, and high‑performing culture that values scientific excellence, operational rigor, and collaboration. To support our continued growth, we are strengthening our workforce strategy to ensure we have the right talent, at the right time, in the right way.

Location:

Conshohocken, PA

Contract Position

The Director, Commercial Real Estate & Workplace Safety will oversee the planning, design, and execution of Madrigal’s new 65,000‑square‑foot corporate office buildout in Conshohocken, PA and 53,000 square‑foot office in Waltham, PA, ensuring the project is delivered on time, within budget, and aligned with company standards. This leader will also develop and implement comprehensive Environmental Health & Safety (EHS), OSHA compliance, and ergonomics programs to support a safe, sustainable, and productive workplace environment that align with real estate, facilities, and employee experience objectives.

This is a hands‑on leadership role requiring strong project management, vendor oversight, construction administration, and strategic facilities planning experience within a corporate setting (no labs or manufacturing).

• Lead the day‑to‑day coordination of the corporate offices projects —from design and permitting through construction, occupancy, and post‑move stabilization ensuring alignment with overall real estate strategy and design standards established by Executive Director
• Manage cross‑functional project activities across architecture, design, engineering, and construction partners to keep deliverables on track and within scope.
• Oversee project logistics including budget tracking, documentation, RFP coordination, change order processing, maintaining transparency and accountability.
• Partner with IT, HR, and Finance to ensure technology, workspace design, and budget alignment.
• Monitor project schedules and milestones, ensuring timely delivery and proactive issue resolution.
• Coordinate move management, furniture procurement, signage, and occupancy planning.

• Develop and implement a comprehensive EHS program for corporate office operations (no lab/manufacturing scope).
• Ensure compliance with OSHA, local building codes, and other applicable regulations.
• Lead ergonomics assessments and programs to enhance employee health, safety, and comfort.
• Partner with HR and Facilities to drive workplace safety training and emergency preparedness initiatives.
• Establish metrics, audits, and continuous improvement programs for safety performance.
• Oversee sustainability and environmental initiatives aligned with corporate responsibility goals, both domestically and internationally.

• Coordinate global real estate operations including lease documentation, renewals, data management, ensuring portfolio accuracy and compliance. Contribute to the evolution of Madrigal’s workplace strategy that supports growth, employee experience, and hybrid work models.
• Support long‑term space planning and real estate portfolio management frameworks.
• Manage relationships with property owners, landlords, and key vendors.
• Lead workplace policy development around space usage, health & safety, and…