Finance Systems Manager

Opportunity awaits those up to the challenge of developing transformative therapies across a broad range of debilitating diseases.

The Finance Systems Manager is responsible for owning, supporting, and optimizing the company’s finance and accounting systems, with a primary focus on SAP S/4

HANA. This role partners closely with Accounting, FP&A, and IT to ensure financial systems accurately support accounting operations, financial close, reporting, and internal controls while driving continuous improvement and systems optimization. The ideal candidate brings a strong combination of accounting knowledge, systems expertise, and cross functional collaboration to help drive system reliability, process efficiency, and data integrity to support business growth.

• Serve as the primary finance systems lead for SAP S/4
  
  HANA and other core finance and accounting systems
• Own finance master data governance, including Chart of Accounts, company codes, profit centers, cost centers, and business partners
• Partner with Accounting to support month‑end close and financial reporting processes
• Coordinate system enhancements, configuration changes, and issue resolution with IT and external SAP partners
• Translate accounting and business requirements into functional system solutions
• Ensure system configuration aligns with accounting policies and business requirements
• Develop and maintain system documentation, controls, and process flows to support SOX compliance
• Support testing, validation, and deployment of SAP releases, upgrades, and new functionality
• Provide user support, training, and process guidance to finance stakeholders
• Support financial reporting, ad hoc analysis, and audit requests
• Support new entity setup, reorganizations, and system‑related accounting changes as needed
• Lead or support finance system projects and continuous improvement initiatives
• Perform other projects as assigned

• Bachelor’s degree in Accounting, Finance, Information Systems or related field
• 5+ years of experience in accounting systems, finance systems, or ERP support
• Strong understanding of accounting principles and financial close processes
• Deep SAP S/4
  
  HANA FICO knowledge and hands‑on experience with configuration and master data is required
• Experience supporting multi‑entity and multi‑currency environments preferred
• Experience in a SOX‑controlled environment preferred
• Advanced Excel skills; experience with reporting tools a plus
• Experience with accounting and finance systems such as Flo Qast, Audit Board, Adaptive Insights, Concur, alteryx, etc. is a plus

• Knowledge of relevant systems
• Proficiency with Microsoft Outlook, Word, Excel, Teams, etc.
• Demonstrated skills in project and program management
• Demonstrated complex problem‑solving ability and sound judgement ability
• Strong organizational, communication and interpersonal skills
• Demonstrate ability to work independently and collaborate to resolve issues
• Highly organized, results driven, problem solver
• Superior written and oral communication skills and the ability to work across different levels of management

10% travel

Bachelor's Degree

Base salary for this role will consider multiple factors, including but not limited to, candidate qualifications, relevant expertise, specialized skills, and industry experience in complement-targeted therapies. The targeted base salary range for this position is $124,000‑$185,000. This range represents the base salary only and reflects Apellis' commitment to competitive compensation within the biopharmaceutical industry. The final salary offered may vary based on individual qualifications, business needs, and current market conditions.

Apellis offers a comprehensive benefits package, including a 401(k) plan with company match, inclusive family building benefits, flexible time off, summer and winter shutdowns, paid family leave, disability and life insurance, and more! Visit  to learn more.

Apellis Pharmaceuticals, Inc. is a global biopharmaceutical company leading the way in complement science to develop…