Associate Research Scientist – Protein Mass Spectrometry

Overview

Each of us cares about someone who will need medicines. That’s why our vision is to repeatedly beat the odds to deliver breakthrough medicines to patients that need them. We pursue truth and scientific rigour and have the courage to work at the edge of the unknown.

We are looking for a highly motivated Associate Research Scientist with demonstrated hands‑on experience using mass spectrometry and other analytical techniques to join our team for a 12‑month fixed term. You will focus on the characterization of therapeutic small molecules, antibodies and/or other proteins, while working in a fast‑paced, collaborative environment and interacting with a diverse team of scientists.

• Performing LC‑MS methods for quantitation and characterization of small molecule compounds and/or antibodies or other proteins.
• Evaluating and recording performance metrics for LC‑MS platforms and assays.
• Documenting results in an ELN and communicating across a matrix team.
• Assisting with various analytical laboratory activities, including compound inventory, LC‑MS instrument operation, maintenance, and troubleshooting.
• Assisting with assay development, including method validation and optimization.
• Performing routine and advanced bioanalytical assays to support in‑vitro activities.
• Developing and implementing standard operating procedures.
• Organizing, supporting, and collaborating with team members to meet project deliverables and timelines.

• You have a MSc in Analytical Chemistry, Biochemistry, or a related field, or you have a BSc with 3+ years of relevant wet‑lab experience in an academic or industry setting.
• You have hands‑on experience preparing and analyzing organic compounds, metabolites, or other ADC‑related small molecules using LC‑MS workflows.
• You have experience with analytical and scientific software such as Chromeleon, Trace Finder, Compound Discoverer, Chem Draw, Prism.
• You have hands‑on experience operating LC‑MS instrumentation including QQQ, Q‑TOF, or Orbitrap MS systems.
• You are able to implement methods for high‑throughput sample preparation and automated data analysis, and have experience in method qualifications and drafting SOPs.
• You have experience with other small molecule analytical techniques such as NMR or IR Spectroscopy. Familiarity with large‑molecule analytical techniques such as UHPLC, CE‑SDS, SEC‑MALLS, DLS, or icIEF would also be welcome.
• You think critically, are curious, and want to explore new technologies and opportunities to improve antibody characterization workflows and processes.
• You are a creative problem solver and fast learner who believes in team work to tackle the most challenging scientific problems.
• You have great interpersonal skills, and thrive in a collaborative working environment as a member of a cross‑functional team.
• You have excellent documentation, organizational, and communication skills, impeccable attention to detail, and an ability to analyse and interpret large datasets.

AbCellera’s hiring range for this role is CAD 61,600 – 77,000 annually, commensurate with your education and job‑related knowledge, skills, and experience. In addition to base salary, we offer equity, annual bonus dependent on team and company performance, and a 6% (non‑match) RRSP contribution.

You will have a CAD 1,500 annual Active Lifestyle Allowance, annual vacation, professional development opportunities, and comprehensive health benefits. Scientific and technical mentorship is a priority. And you’ll find a strong sense of community and connections across AbCellera through our work, clubs, and socials.

Creating medicines is the most important work we can do.

We are a clinical‑stage biotechnology company focused on discovering and developing antibody‑based medicines in the areas of endocrinology, women’s health, immunology, and oncology. We have built a platform for advancing antibody drug programs from target to clinic, and we are using it to build our internal pipeline.

Today, our pipeline includes two drug candidates in clinical development, two preclinical development candidates (DCs) in Investigational New Drug…