Zandstra lab - Non Union - Research Assistant​/Technician

Staff - Non Union Job Category Non Union Technicians and Research Assistants Job Profile Non Union Salaried - Research Assistant /Technician 3 Job Title Zandstra lab - Non Union Salaried - Research Assistant /Technician 3 Department Zandstra Laboratory | School of Biomedical Engineering | Faculty of Medicine Compensation Range $4,567.04 - $5,385.67 CAD Monthly Posting End Date March 22, 2026.

Note: Applications will be accepted until 11:59 PM on the Posting End Date.

Job End Date March 1, 2027.

At UBC, we believe that attracting and sustaining a diverse workforce is key to the successful pursuit of excellence in research, innovation, and learning for all faculty, staff and students. Our commitment to employment equity helps achieve inclusion and fairness, brings rich diversity to UBC as a workplace, and creates the necessary conditions for a rewarding career.

The School of Biomedical Engineering (SBME) at the University of British Columbia (UBC) is a partnership between the Faculties of Applied Science and Medicine, established in 2017. The School is a nucleus for education and training, research, and innovation in biomedical engineering, creating new knowledge, new academic and training programs, and fostering translation and innovation. Its vision is to transform health and healthcare for all, achieved through innovative research and education at the convergence of engineering, medicine and biology.

Through collaborative, innovative, and interdisciplinary approaches and building on UBC’s academic and research excellence, the School of Biomedical Engineering aspires to be a global leader in biomedical engineering research, education and translation. The SBME has two locations on Vancouver’s campus, the Gordon B Shrum building and the Biomedical Research Centre (BRC). For more information about the School of Biomedical Engineering, please visit

The Research Assistant/Technician will report to Principal Investigator in the Zandstra Lab and work collaboratively with other staff, students and postdoctoral fellows.

The technician will work in laboratory and animal facility setting and may be required to work occasional weekend or evening work for time-sensitive experiments. The work involves exposure to animal allergens and biological materials, including immunodeficient mice and human cells. An initial orientation will be provided on biosafety, radiation safety, and animal handling.

• Maintain and manage genetically engineered mouse colonies.
• Monitor animal health and welfare, identify signs of distress, and coordinate veterinary care.
• Maintain accurate breeding and experimental records using colony management software.
• Coordinate routine genotyping.

• Perform humanized mouse model generation, including engraftment of human CD34+ HSCs or immune cell products.
• Sublethal irradiation.
• Perform blood collection via tail vein and cardiac puncture techniques.
• Conduct live bone marrow aspirations (training will be provided).
• Tissue harvests (e.g. bone marrow, spleen, thymus, lymph nodes).
• Administer compounds via oral gavage, intraperitoneal, intravenous, and subcutaneous routes.
• Mice ultrasound.
• Flow cytometry sample preparation, acquisition and analysis (training will be provided).
• Monitor post‑procedure recovery and elevate any concerns to senior researchers.
• Animal/Human primary cell genotyping, extracting DNA, and running qPCR or ddPCR on the samples.

• Assist in pre‑clinical validation studies for cell therapy products.
• Coordinate with bioengineers on experimental design for in vivo efficacy and safety studies.
• Prepare single‑cell suspensions from hematopoietic tissues.
• Process samples for downstream analysis (flow cytometry, histology, molecular biology).
• Maintain detailed experimental logs and contribute to data organization.
• Collaborate with research staff to execute experimental protocols.

• Ensure compliance with institutional animal care guidelines provided by the UBC Animal Care Committee (ACC).
• Maintain sterile technique for immunocompromised mouse handling.
• Follow biosafety and…