Computational Biologist, Database Development, Genome Sciences Centre; GSC - BC Cancer
Job in
Vancouver, BC, Canada
Listing for:
PHSA
Full Time
position
Listed on 2026-01-15
Job specializations:
-
Research/Development
Clinical Research, Data Scientist, Research Scientist
-
Healthcare
Clinical Research, Data Scientist
Job Description & How to Apply Below
Position: Computational Biologist, Database Development, Genome Sciences Centre (GSC) - BC Cancer
Computational Biologist, Database Development, Genome Sciences Centre (GSC)
BC Cancer
Vancouver, BC
The Computational Biologist will participate in the analysis of sequencing data by developing, refining and adapting bioinformatics tools for a high-throughput processing pipeline. The Computational Biologist will also participate in the development and maintenance of the production databases, which provide tracking of all of the laboratory and bioinformatics analysis pipelines at the GSC. Additionally, the Computational Biologist will assist in the packaging and distribution of developed tools and analysis results to the scientific community, and will be contributing to the preparation of scientific publications.
What you’ll do
Assist in the development and maintains the core sequence analysis pipelines at GSC, including but not limited to:o QC of sequencing data;
o Alignment of sequenced reads;
o Formatting and manipulation of alignment files for use by downstream pipelines merging, reheadering);
o Dissemination of data to collaborators;
o New analyses pipelines as required.
Assists in the development and maintains GSC laboratory, quality and analysis databases, including:o Routine database integrity checks and database maintenance;
o Development of views and interfaces for data entry;
o Development of reports for internal users and collaborators;
o Investigation of new frameworks and designing new schemas and tables.
Communicate with stakeholders in the lab, on analysis teams, and with external collaborators to understand and document requirements for development and to respond to questions about collaborator data and data quality.Work with upstream and lab teams generating data to be housed in the database, and with downstream users of the databases to meet requirements, and responds to internal requests for query and API support.Participate in the development and maintains ETL pipelines between GSC production databases.Manage the storage and compression of over 5
Pb of internally generated sequencing data as well as the download and storage of external data.Work closely with GSC Systems team and Quality Assurance team to establish and carry out best practices for data security, and ensure compliance with ISO 27001 certification, CAP/DAP clinical accreditation requirements and other data use agreements.Test and validate new data analysis software for analyses such as alignment, duplicate marking and merging.Participate in code walk-throughs and reviews of solutions.Participate in the design and builds database solutions, taking performance into consideration.Coordinate production problem resolution for assigned applications, including working with other technical teams.Produce thorough but concise written documentation of database tables, applications, validations, SOPs, and other processes and procedures as required.Performs other related duties as required.What you bring
Qualifications:
Graduation from a recognized Bachelor of Science Program in Computer Science or equivalent with significant computer science components.Two (2) years of recent related experience or an equivalent combination of education, training and experience acceptable to the GSC Group Leaders.Demonstrated knowledge of the historic and ongoing impacts of settler colonialism on Indigenous Peoples in social and health contexts, including supported by significant knowledge of Indigenous-specific mandates, including clear understanding of and commitment to eradicate Indigenous-specific racism and discrimination and embed Indigenous Cultural Safety and Humility.Demonstrate comprehensive knowledge of the historic and ongoing impacts of settler colonialism and systemic racism on Indigenous Peoples within social and health contexts. This includes understanding how these factors contribute to current health disparities and barriers to care. Show a clear commitment to identifying, challenging, and eradicating Indigenous-specific racism and all forms of discrimination impacting equity-deserving groups within health care settings.
This involves familiarity and understanding Indigenous Cultural Safety and Humility recognizing personal biases,…
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