About Us
Eupraxia is a clinical‑stage biotechnology company focused on developing locally delivered, extended‑release products that have the potential to address therapeutic areas with high unmet medical need. Diffu Sphere™, a proprietary, polymer‑based micro‑sphere technology, is designed to facilitate targeted drug delivery of both existing and novel drugs. The technology supports an extended duration of effect and delivery of drugs in a hyper‑localized fashion, targeting only the tissues that physicians want to treat.
By achieving precision targeting and stable, flat delivery of the active ingredient, Diffu Sphere™ may reduce adverse events compared with traditional drug delivery methods. This platform has the potential to augment and transform FDA‑approved drugs, improving safety, tolerability, efficacy and duration of effect. Eupraxia is currently developing treatments beyond pain and inflammatory gastrointestinal disease—including oncology, infectious disease and other critical disease areas.
Eupraxia’s EP‑104GI is in a Phase 1b/2a trial (RESOLVE) for the treatment of eosinophilic esophagitis (EoE). The product is administered as an injection into the esophageal wall for local delivery—a unique approach in this therapeutic area. EP‑104
IAR, completed in a Phase 2b trial (SPRINGBOARD) for pain due to knee osteoarthritis, met its primary endpoint and three of four secondary endpoints. The company is also expanding a pipeline of later and earlier‑stage long‑acting formulations for inflammatory joint indications and oncology. For further details visit
We are looking for someone who wants to thrive in a fast‑paced, growing company that fosters a creative spirit and integrated teamwork and who is eligible to work in Canada.
Job DescriptionThe Process Development Scientist will be responsible for developing manufacturing processes for novel solid and viscous liquid formulations in our Vancouver laboratory. The role focuses on process scale‑up and technology transfer to contract manufacturing facilities. This laboratory‑based position expects 80% of work time to be spent on‑site.
Reports to:
Director, CMC
Location:
Vancouver, BC
- Design, plan and execute experiments in the Vancouver Laboratory to support the development of novel solid and viscous liquid formulations.
- Develop and/or evaluate appropriate sterilization procedures, including sterile filtration or terminal sterilization by heat and gamma irradiation.
- Scale up manufacturing processes from laboratory to >100L scale for transfer to contract manufacturer sites.
- Engage in technology transfer and production troubleshooting at contract manufacturer sites.
- Identify and procure equipment required for scale‑up and laboratory operations.
- Perform physical characterization of samples as required (e.g., rheology, viscoelastic analysis, NMR, SEM, thermal analysis). Ability to operate HPLC/UPLC systems and develop analytical methods is an asset.
- Provide training and supervision to co‑op and intern students.
- Interpret and present research findings in a clear, concise manner at company meetings and via written reports.
- Support writing of appropriate sections of regulatory filings, including an IND or IMPD.
- Comply with required Quality Management System procedures, including maintenance of a laboratory notebook.
- Maintain laboratory equipment in a functional status and perform other laboratory duties as needed.
- Assist with CMC group operations as requested.
- Highly self‑motivated
- Able to work independently and as part of a study team
- Detail‑oriented with a view to the overall scope of the project
- Organized
- Accountable
- Self‑directed learner
- At least 5 years of experience in the pharmaceutical industry.
- PhD in chemistry, biochemistry, or pharmaceutical sciences. Candidates with an MSc or a BSc and industry experience will be considered.
- Experience with viscous liquids compounding techniques.
- Experience with sterile filtration and terminal sterilization by autoclave is an asset.
- Experience with aseptic techniques is an asset.
- Knowledge and experience with GMP practices is an asset.
- Excellent verbal and written communication skills.
- A…
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