Principal Scientist

Recruitment Consultant @ S3 Science Recruitment | Headhunting, Drug Discovery Recruitment
About the Role

We are looking for a Principal Scientist in Immunology to provide scientific leadership across our drug discovery programs. You will be responsible for shaping immunology strategy from target identification through to preclinical development, translating deep immune biology into innovative therapeutic approaches.

This role suits an experienced immunologist who enjoys combining hands‑on science with strategic influence and cross‑functional leadership.

Key Responsibilities

Lead immunology strategy across one or more drug discovery programs

Drive target identification, validation, and mechanism‑of‑action studies within immune‑mediated disease areas

Design, oversee, and interpret complex in vitro and in vivo immunology studies

Act as a scientific expert in immune pathways, cell signaling, and disease biology

Partner closely with chemistry, DMPK, translational, and bioinformatics teams

Guide and mentor scientists, fostering strong experimental thinking and scientific rigor

Present scientific data and program strategy to senior leadership and governance forums

Support external collaborations with CROs and academic partners

Required Experience & Skills

PhD in Immunology, Biology, Pharmacology, or a related life science

Significant industry experience in drug discovery immunology

Proven track record of progressing targets or programs through discovery stages

Strong understanding of immune mechanisms, pathway biology and experimental models

Experience leading projects and influencing cross‑functional teams

Excellent communication skills and ability to translate complex biology into clear decisions

Experience in autoimmune, inflammatory, oncology‑immunology, or immuno‑oncology research

Familiarity with translational immunology, biomarkers and patient‑relevant models

Experience managing external vendors or collaborations

Why Join Us

Opportunity to shape immunology strategy at a senior scientific level

Science‑driven, collaborative culture

Competitive salary and benefits

Real impact on the development of next‑generation immune‑targeted therapies

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