Manufacturing Associate, Drug Substance - Shift Position

Overview

The Role and Moderna opportunity involve joining a pioneering team revolutionizing medicine through mRNA technology with a diverse pipeline across diseases. You’ll be part of a growing organization, working with exceptional colleagues and strategic partners worldwide to contribute to global health initiatives. Moderna aims to establish a leading-edge research, development, and manufacturing facility at Harwell for onshore mRNA vaccine production for respiratory diseases, creating skilled jobs and collaborating with academic, NHS, and government partners in the UK.

We are seeking global experts to join this endeavour and help make life-saving vaccines accessible to all.

As a Manufacturing Associate at our Harwell site, you will operate cutting-edge production equipment supporting the safe and effective manufacture of Moderna’s mRNA vaccines. You will work in compliance with cGMP and health and safety regulations, ensuring batch quality and process integrity. The role combines scientific and operational expertise with digital fluency, requiring attention to detail, rapid learning, and collaborative teamwork.

You will contribute to innovations and continuous improvement in a technologically advanced production environment central to Moderna’s mission.

Your key responsibilities will be:

• Operate and monitor production equipment while adhering to cGMP, SOPs, and health and safety procedures
• Maintain a clean, compliant, and safe work environment through gowning and housekeeping standards
• Execute operations and maintain accurate manufacturing documentation for batch disposition
• Perform routine equipment maintenance such as lubrication, filter changes, and mechanical checks using hand-tools
• Troubleshoot digital and equipment-related issues rapidly and efficiently
• Keep training records and operational logs up to date, ensuring full compliance
• Work flexibly including off-hours or overtime to support manufacturing schedules
• Take part in deviation investigations (RCA), CAPA tasks, and contribute to incident analyses
• Collaborate closely with QA and cross-functional teams to meet production KPIs

Your responsibilities will also include:

• Promote safe work habits in alignment with Moderna’s safety culture
• Proactively identify and report safety or compliance concerns to leadership
• Participate in multiple projects and continuous improvement initiatives
• Apply lean tools and digital platforms to drive operational excellence
• Engage in a fast-paced, matrixed work environment with agility and a problem-solving mindset

The key Moderna Mindsets you’ll need to succeed in the role:

• We digitize everywhere possible using the power of code to maximize our impact on patients. Your comfort in using digital tools and platforms will be essential in Moderna’s highly automated production environment. From troubleshooting to operational logging, you’ll be expected to leverage technology to enhance efficiency and product integrity.
• We behave like owners. The solutions we’re building go beyond any job description. In this role, every team member is expected to step up with initiative and accountability. You’ll own your area of operation and contribute beyond task execution, seeking opportunities to improve workflows and patient outcomes through proactive problem-solving.

• 1+ years of experience in a GMP manufacturing environment
• This position is site-based and full-time on Moderna’s site; remote work is not eligible
• As part of Moderna’s commitment to workplace safety, this role may require an enhanced pre-employment check

• A university degree with a specialization in Pharmaceutical production technology or equivalent
• Experience with filtration and chromatography, and cold chain management a plus
• Experience in audit/inspection preparation, understanding health authority and regulatory guidelines
• Ability to collaborate fluidly with peers, leadership and cross-functional support groups
• Excellent written, oral communication, and organizational skills
• Ability to maintain attention to detail while executing multiple tasks with minimal supervision
• Demonstrated commitment to Moderna's values of Bold,…