Scientist LC- MS Bioanalytical - Thousand Oaks, CA

Job Description

ATTENTION MILITARY AFFILIATED JOB SEEKERS – Our organization works with partner companies to source qualified talent for their open roles. The following position is available to Veterans, Transitioning Military, National Guard and Reserve Members, Military Spouses, Wounded Warriors, and their Caregivers. If you have the required skill set, education requirements, and experience, please click the submit button and follow the next steps.

Unless specifically stated otherwise, this role is “On‑Site” at the location detailed in the job post.

In this vital role, you will support the design, development, validation, and implementation of robust LC‑MS/MS bioanalytical methods for a wide range of therapeutic modalities—including small molecules, oligonucleotides, proteins, and other complex molecular entities—to enable GLP preclinical and regulated clinical studies. Given the scope of projects, the role will involve multidisciplinary interactions with scientists across research and development  position is lab‑based, and has significant emphasis on data management/fidelity, report generation, effective time management, communication, and data presentation.

Responsibilities include:

• Perform quantitative bioanalytical experiments, organize data and results, including planning and running LC‑MS/MS bioanalysis and preparing and analyzing biological samples.
• Develop and implement LC‑MS/MS bioanalytical methods with quick turnaround times.
• Conduct small and large molecule bioanalysis in non‑clinical and clinical samples from various matrices (plasma, urine, CSF, tissues).
• Perform biological sample extraction using protein crash (PPT), SPE, LLE, and/or affinity capture methodologies.
• Generate complete, accurate, and concise documentation using electronic systems and laboratory notebook.
• Ensure bioanalytical data meets regulatory expectations for global submissions by maintaining accurate records and staying current with industry guidelines.
• Author study reports, standard operating procedures, analytical methods, memos, and other regulatory‑compliant documents.
• Communicate bioanalytical data to key discovery and development teams, contribute to scientific publications, and present at professional meetings.
• Comply with safety guidelines and site‑specific procedures, including training, laboratory documentation, and SOP adherence.
• Perform general laboratory housekeeping activities and operational support as needed, including QC of reports.

467151

Bachelor's

• Doctorate degree
• OR Master’s degree and 2 years of relevant industrial/technical experience
• OR Bachelor’s degree and 4 years of relevant industrial/technical experience

• Prior experience in CRO or pharma/biotech strongly desired.
• Strong technical expertise in quantitative mass spectrometry on triple quadrupole (QQQ) platforms as well as HRMS.
• Experience with an array of analytical technologies that can accelerate bioanalysis inclusive of automation and/or micro‑sampling.
• Prior GLP and GCP experience.
• Demonstrated expertise in working with a variety of sample types (e.g., blood, plasma, serum, tissues, cerebrospinal fluid) and employing diverse sample preparation techniques (e.g., SPE, LLE, immunocapture) to support analysis of different therapeutic modalities, including small and large molecules by LC‑MS.
• Prior experience in bioanalytical (regulated) assay execution and transfer to CROs.
• Must be willing to work in a fast‑paced, multi‑project environment with high workload demands, and consistently deliver high‑quality results within established timelines.
• Demonstrated ability to resolve scientific challenges efficiently and prioritize effectively.
• Excellent scientific problem‑solving skills.
• Excellent project and time‑management abilities.
• Ability to work collaboratively with internal and external stakeholders.
• Supervisory and mentoring experience in a lab‑based setting.

USD –  USD

Thousand Oaks, California

Pharmaceutical Pharmaceutical

Amgen