Research Specialist

Job Profile Summary

Provides technical lab support by independently performing basic lab and research-related tasks to ensure accurate research results that can expand on the knowledge of the field of study. Responsible for following lab safety standards.

We invite applications for an NIH-funded Research Specialist position to join a highly collaborative and multidisciplinary research team focused on studies of intestinal stem cells, early developmental programming, and oncogenic transformation using genome editing methods with multi-omic approaches. The successful candidate will lead projects aimed at dissecting the developmental programming of intestinal stem cells using human iPSC‑derived colon organoids. The position offers an exciting opportunity to work at the interface of developmental and stem cell biology, tumor initiation, and single‑cell methods.

The research involves human iPS cell culture, genome editing, in vitro directed differentiation, modeling of early events in colorectal cancer, and multi‑omic applications. Anticipated start is Spring 2026, but remains flexible for applicants with desired qualifications. This position is expected to run for at least two consecutive years. The second‑year renewal is contingent upon satisfactory progress and contribution to the collective program.

About the PI:
Miyeko

D. Mana is an assistant professor in the School of Life Sciences at Arizona State University and a research affiliate at Mayo Clinic Arizona. She is an American Cancer Society Research Scholar with over 2900 citations, known for her contributions to understanding how diets affect intestinal stem cells using mouse and organoid models.

About the Lab:
The lab explores how intestinal stem cells are influenced by environmental factors that promote or protect against intestinal pathologies. The focus is the metabolic‑transcriptional‑epigenetic axis that governs stem cell intrinsic adaptations to diet. The lab is part of the larger regenerative biology and regenerative medicine community studying basic and biomedical questions.

• Performing experiments
• Data analysis
• Manuscript preparation
• Collaborating effectively with members of the lab.

• Strong knowledge in stem cell biology, differentiation, gene regulation.
• Track record of peer‑reviewed publications commensurate with experience.
• Experience with iPSC culture and genome editing tools.
• Basic computation skills in R or Python, with an interest in increasing proficiency for single cell applications and analysis.
• Ability to work independently and collaboratively.
• Demonstrated commitment to working with faculty, staff, students, and communities to advance the principles of the ASU Charter.

• Training in epigenetics, developmental biology, molecular genetics.
• Experience with in vivo models and organoid cultures.
• Proficiency with single‑cell applications including analysis.
• Demonstrated curiosity, motivation, and scientific rigor.
• Effective communication skills.
• Interest in mentoring graduate students and undergraduates.

Activities are performed in an office and lab setting subject to extended periods of field work, sitting, keyboarding, and manipulating a computer mouse, and standing for varying lengths of time. May be required to wear personal protective equipment before entering laboratories such as lab coat, gloves, safety glasses, closed toe shoes, and respirator. Frequent bending, reaching, lifting, pushing, and pulling up to 25 pounds.

Ability to clearly communicate to perform essential functions. This position receives regular review of objectives by department administrator.

To be considered, your application must include all of the following attachments:

• Cover letter
• Resume/CV

Note:

Multiple documents can be submitted into the attachment box. Alternatively, merge all documents into one PDF for submission. Please include all employment information in month/year format (e.g., 6/88 to 8/94), job title, job duties and name of employer for each position. Resume should clearly illustrate how prior knowledge and experience meets the Minimum and Desired qualifications of this position.

NOTE:

GA and Intern positions are counted as .5 for job experience (ie. 1 year equals 6 months experience equivalency). Only electronic applications are accepted for this position.

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, protected veteran status, or any other basis protected by law.

Position Salary Range: $50,000 - $72,900; DOE.

Time Type:
Full time.