Manager, Value Stream Cryo Operations

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Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it.

You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more at

At Bristol Myers Squibb we are reimagining the future of cell therapy. With our bold ambition, backed by a best-in-the-industry team and long-term commitment, we are leading the way to unlock the full promise of cell therapy as we strive to put more patients on the path to a cure. If you are ready to challenge yourself, accelerate your career, and give new hope to patients, there's no better place than here at BMS with our Cell Therapy team.

The Manager, CAR T Value Stream Cryo Operations leads a team of Specialists, Team Leads and Associates responsible for all processes associated with Cryopreservation and Sample Management, Frozen Process Material Retrieval, Movement, and Storage within CAR T clinical and commercial operations in a cGMP multi-cleanroom suite. This role plays a critical part in ensuring production continuity, traceability, and compliance across multiple shifts in a 24/7 operation.

The Manager is accountable for driving operational excellence, ensuring compliance with all regulatory requirements (FDA, DEA, DOT, ISBT, CTPAT, OSHA, VAWD, cGMPs), and fostering a culture of safety, collaboration, innovation, and continuous improvement.

• Wednesday - Saturday (with e/o Wednesday off), Onsite Overnight Shift, 5 p.m.
  
  - 5:30 a.m.

• Lead Cryopreservation and handling of all Cell Therapy Products across multiple production areas and shifts.
• Ensure execution of production tasks in alignment with cGMPs, SOPs, and Work Instructions while maintaining complete traceability.
• Oversee Material Retrieval, Movement, Storage, and Inventory Management within Cryotanks and Controlled Rate Freezers (CRFs).
• Maintain hands‑on expertise in Unit Operations, role model good execution and behaviors, and backfill resources if needed.
• Provide production scheduling team with daily, weekly, and monthly updates on resource availability and task execution.
• Lead batch record reviews (BRR) and ensure all documentation follows ALCOA+ principles.
• Drive adherence to all training requirements, ensuring team members are proficient and qualified.
• Recruit, train, and develop a high‑performing team of Managers, Leads, and Associates.
• Set and adjust team priorities to align with site and functional objectives.
• Conduct regular 1:1 meetings to mentor and support team members’ professional development.
• Own the performance review process, provide continuous feedback, and recognize achievements.
• Foster a culture of accountability, ethics, and decision‑making within the team.
• Champion lean principles to improve efficiency and eliminate non‑value‑added activities.
• Lead troubleshooting activities and own Deviation Management, ensuring timely documentation and closure.
• Monitor deviation metrics, identify repeat causes, and drive corrective actions.
• Participate in projects, change controls, and CAPAs to enhance compliance and operational performance.
• Participate and lead in process improvement projects within the department.
• Build strong cross‑functional relationships to drive collaboration and alignment with stakeholders.
• Control operational expenses (OT, Supplies, T&E) and identify cost‑saving opportunities.
• Take personal…