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Senior Director, Health Economics and Outcomes Research

Job in South San Francisco, San Mateo County, California, 94083, USA
Listing for: IDEAYA Biosciences
Full Time position
Listed on 2026-01-25
Job specializations:
  • Software Development
    Data Scientist, Data Science Manager
Job Description & How to Apply Below
Position: Senior Director, Health Economics and Outcomes Research / Real World Evidence

Non-Solicitation Policy And Notice To Agencies And Recruiters

IDEAYA's Non-Solicitation Policy strictly prohibits agencies and recruiters from any contact and communication with IDEAYA employees, managers, and leaders to submit unsolicited candidate resumes and/or to solicit business partnerships. Submission of unsolicited candidate resumes by agencies or recruiters with or without a contract in place with IDEAYA Biosciences Inc. will not create any implied obligation. Failure to comply with this policy will result in disqualification from current and future business opportunities with IDEAYA Biosciences.

All recruiting and talent agency decisions are strictly managed by the internal IDEAYA Human Resources function. All communication by external agencies and recruiters must be directed to  We ask that you only email your interest once.

Job Summary

About IDEAYA Biosciences: IDEAYA is a precision medicine oncology company committed to the discovery, development, and commercialization of transformative therapies for cancer. Our approach integrates expertise in small-molecule drug discovery, structural biology and bioinformatics with robust internal capabilities in identifying and validating translational biomarkers to develop tailored, potentially first-in-class targeted therapies aligned to the genetic drivers of disease. We have built a deep pipeline of product candidates focused on synthetic lethality and antibody-drug conjugates, or ADCs, for molecularly defined solid tumor indications.

Our mission is to bring forth the next wave of precision oncology therapies that are more selective, more effective, and deeply personalized with the goal of altering the course of disease and improving clinical outcomes for patients with cancer.

When you're at IDEAYA, you will be in the midst of brilliant minds working on precision medicine therapies to help cancer patients. We are passionate and committed about being on the forefront of oncology medicine, which means we all have a high internal drive that is at the very core of every person  are inquisitive, ask deep questions, and are data-driven innovators who like to collaborate and use teamwork to move science forward.

For more information, please see

Location:

South San Francisco, CA.

Position Summary

We are seeking a Senior Director of Health Economics and Outcomes Research / Real World Evidence (HEOR/RWE) to join the IDEAYA Commercial team. The Senior Director, HEOR/RWE will be responsible for shaping and executing IDEAYA’s health economics, outcomes research, and real-world evidence strategy for the launch of darovasertib in metastatic uveal melanoma (mUM). This leader will play a pivotal role in generating evidence in a very high unmet disease area for payers, providers, and patients.

They will have an opportunity to take innovative approaches to value demonstration in orphan diseases, biomarker-driven populations, and unique combination treatments. While the initial focus will be on darovasertib, this role will evolve over time to include direct reports and contribute on the global launches of IDEAYA’s exciting pipeline of oncology assets.

This position is based in our South San Francisco headquarter offices and required to be onsite four days per week per our company policy.

Reporting to:
Vice President, Value and Access

Job Description

What you’ll do:

  • Develop and execute the HEOR and RWE strategy to support US value demonstration for darovasertib at launch and through its lifecycle
  • Collaborate with Market Access, Medical Affairs and Clinical Development to evaluate data gaps and develop robust evidence generation and publication plans
  • Develop and execute core evidence-generation activities including chart reviews, literature reviews, PRO studies, and micro-costing analyses to strengthen the clinical and economic differentiation of the product
  • Design and implement real-world data analyses to articulate the current patient demographics, treatment patterns, and outcomes for mUM patients
  • Develop comprehensive health economic model analyses to demonstrate value, inform pricing strategy, and support reimbursement decisions
  • Partner with Market Access to develop robust and compelling clinical, humanistic, and economic value propositions and oversee development of AMCP and Global Value Dossiers
  • Lead the external dissemination of HEOR/RWE deliverables including publications, presentations, and professional conferences
  • Develop, train, and implement the resources that support field HEOR efforts with key customers; ensure programs and materials comply with SOPs and Medical, Legal & Regulatory (MLR) reviews
  • Engage and collaborate with external partners including payers, providers, and other access decision-makers to establish / maintain strong partnerships and gather insights
  • Support field team engagements during Preapproval Information Exchange (PIE) and post-approval interactions to educate payers and provider access stakeholders on darovasertib
  • Stay current with advancements in…
Position Requirements
10+ Years work experience
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