Director, Medicinal Chemistry

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About IDEAYA Biosciences: IDEAYA is a precision medicine oncology company committed to the discovery, development, and commercialization of transformative therapies for cancer. Our approach integrates expertise in small-molecule drug discovery, structural biology and bioinformatics with robust internal capabilities in identifying and validating translational biomarkers to develop tailored, potentially first-in-class targeted therapies aligned to the genetic drivers of disease. We have built a deep pipeline of product candidates focused on synthetic lethality and antibody-drug conjugates, or ADCs, for molecularly defined solid tumor indications.

Our mission is to bring forth the next wave of precision oncology therapies that are more selective, more effective, and deeply personalized with the goal of altering the course of disease and improving clinical outcomes for patients with cancer.

When you're at IDEAYA, you will be in the midst of brilliant minds working on precision medicine therapies to help cancer patients. We are passionate and committed about being on the forefront of oncology medicine, which means we all have a high internal drive that is at the very core of every person  are inquisitive, ask deep questions, and are data-driven innovators who like to collaborate and use team work to move science forward.

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Location:

South San Francisco, CA

Position Summary:

We are seeking a talented and highly motivated individual with significant pharmaceutical industry experience to join our multidisciplinary team. The successful candidate will lead projects to drug challenging, structurally-enabled, first-in-class targets employing your expertise in structure-based design paired with our world-class computational and structural chemistry groups. Your job responsibilities will involve cross-functional collaboration and communication up and down the organization to lead discovery programs and drive the internal oncology portfolio.

As a senior member of the chemistry team, you will manage and mentor junior chemists and other scientists across the organization You will also be directly responsible for managing external chemistry partners to ensure the rapid preparation of target molecules and identifying new technologies to bring into the organization.

This position is based in our South San Francisco headquarter offices and required to be onsite four days per week per our company policy.

Reporting to:
Senior Director, Medicinal Chemistry

What you’ll do:

• Serve as project lead for challenging first-in-class small molecule projects
• Collaborate closely with other research functions and with leadership to craft project strategies and deliver on project goals
• Clearly communicate strategy and results across the organization
• Manage and mentor direct report(s) and manage external FTEs to high productivity
• As part of the department leadership team, help craft and execute department strategy
• Monitor new developments in the field and identify new technologies to bring to the organization

Requirements:

• Ph.D. in synthetic organic chemistry with 10+ years pharmaceutical medicinal chemistry industrial experience
• Demonstrate a strong record of delivering portfolio success and driving projects through to the identification of high quality…