Senior Scientist, Computational Chemistry

** Job Description
** Our Company's Research Laboratories located in South San Francisco are a thriving hub for discovery research. Located in the heart of the Bay Area’s biomedical community, our research ranges from exploratory biology to early clinical development. We work on diverse modalities – small molecules, peptides, bioconjugates and biologics. Our laboratories are an integral part of our Company's influential network of drug and vaccine discovery.

Join our diverse, inclusive, respected, and collaborative organization where every employee contributes to our critical mission of discovering drugs. At our Company's Research Laboratories, you’ll have the opportunity to expand your knowledge, develop your skills, and advance your career while working with the best minds in the industry.
*
* The Role:

** We are seeking candidates preferably with:
* Familiarity with one or more molecular modeling packages such as MOE, Schrodinger, Open Eye
* Proficiency in applying computational methods such as molecular dynamics, quantum chemistry, and machine learning to biological problems
* Cheminformatics experience to analyze and understand data
*
* Key Responsibilities:

*** Collaborate with multidisciplinary teams to discover new drugs
* Spearhead the modeling and informatics initiatives on project teams, strategically applying computational methodologies throughout all stages of the drug discovery process.
* Utilizing various informatics and modeling techniques to analyze large datasets and accelerate the evolution of drug discovery leads to drug candidates.
* Engaging in research in areas of molecular modeling relevant to drug discovery and maintaining an external scientific presence through significant scientific publications and presentations
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* Qualifications:

***
* Education:

*** Ph.D. (or completion by July 2026) in Computational Chemistry, Biophysics, Chemistry, Biochemistry or related field and relevant experience
** Required

Experience and Skills:

*** Programming/scripting proficiency in Python, including experience manipulating large datasets
* Familiarity with Linux and high-performance computing
* Strong written and oral communication skills, and ability to work well in multidisciplinary teams
* Evidence of creative application of computational chemistry approaches to problems of biological interest, demonstrated through multiple publications and external presentations
** Preferred

Experience and Skills:

*** Experience applying computational methods such as molecular dynamics, quantum chemistry, and deep learning to problems of biological interest
* Experience with lead identification and lead optimization of diverse therapeutic modalities
* Ability to use molecular modeling packages such as MOE, Schrodinger, and Open Eye
* Have experience with Cheminformatics tools such as Spotfire to analyze and visualize the data
* Excited to learn and implement novel technologies including AI/ML to advance the pipeline
* Experience working in multidisciplinary teams that include experimental scientists  #EligibleforERP
*
* Required Skills:

** Biochemistry, Biophysics, Chemistry, Computational Chemistry, Data Science, Drug Discovery Process, High Performance Computing (HPC), Informatics, Linux, Machine Learning (ML), Molecular Modeling, Python (Programming Language), Quantum Chemistry, Scientific Modeling
** Preferred

Skills:

** Current Employees apply

Current Contingent Workers apply
** US and Puerto Rico Residents Only:
** Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please  if you need an accommodation during the application or hiring process.

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics.  As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities.  

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