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Research Technician II

Job in South San Francisco, San Mateo County, California, 94083, USA
Listing for: Astrix
Contract position
Listed on 2026-02-01
Job specializations:
  • Research/Development
    Research Scientist, Biomedical Science
Job Description & How to Apply Below

Overview

A leading research organization is seeking a Research Technician II to support cutting-edge functional genomics projects focused on large-scale, high-throughput DNA cis-regulatory element screening.

Job Details

Job Title: Research Technician II – Functional Genomics

Location: On-site, South San Francisco, CA

Duration: 6-month contract with potential extension (Benefits included)

Responsibilities
  • Perform complex molecular and cellular biology experiments in functional genomics
  • Support massively parallel reporter assay (MPRA) screens across multiple cell types
  • Conduct custom DNA/RNA amplicon preparation and sequencing workflows
  • Execute molecular biology techniques including molecular cloning, qPCR, and flow cytometry
  • Maintain and work with primary cell cultures, with preference for iPSC and/or T cell culture experience
  • Assist in experimental design, data interpretation, and results communication
  • Contribute to development and optimization of genomics screening technologies
Qualifications
  • Bachelor’s, Master’s, or PhD in Biology, Genetics, Biomedical Engineering, or a related field
  • 2–5 years of relevant laboratory experience
  • Strong experimental design and data analysis skills
  • Highly organized, analytical, and self-motivated
  • Excellent communication and teamwork abilities
Preferred Technical Experience
  • MPRA or other pooled genetic screening approaches
  • Viral vector systems (e.g., lentivirus)
  • NGS library preparation and design
  • Single-cell genomics methods such as scRNA-seq or scMPRA
What This Role Offers
  • Hands-on experience with state-of-the-art functional genomics technologies
  • Exposure to high-throughput screening and machine learning–driven research
  • Opportunities for professional development, mentorship, and scientific learning
  • Must be authorized to work in US without sponsorship.



Note:

This refinement preserves the essential job information while removing duplicated/pay-line noise and formatting inconsistencies from the original description.

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