Research Assistant – Synthetic Molecule Pharmaceutical Sciences; Chemistry Automation

Software Guidance & Assistance, Inc., (SGA), is searching for a Research Assistant – Synthetic Molecule Pharmaceutical Sciences (Chemistry Automation) for a contract assignment with one of our premier Pharmaceutical clients in South San Francisco, CA
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The Research Assistant will join the Chemistry Automation team within Synthetic Molecule Pharmaceutical Sciences, supporting early-phase small-molecule drug development through high-throughput, automation-enabled experimentation. This role focuses on the design, execution, analysis, and documentation of synthetic and analytical experiments using advanced robotic platforms and state-of-the-art characterization tools.

• High-Throughput Experimentation & Automation
• Design, set up, and execute high-throughput screening (HTS) experiments for reaction optimization, solubility, crystallinity, polymorph, and solid-form screening
• Operate and support robotic and automated laboratory platforms, liquid handlers, and integrated analytical systems
• Prepare samples, reagents, and plates in accordance with established SOPs and safety requirements
• Analytical Characterization & Data Generation
• Perform compound characterization using advanced analytical techniques, including XRPD, microscopy, UHPLC/HPLC, MS, and SFC
• Analyze, interpret, and document experimental data in electronic lab notebooks (ELNs)
• Partner with subject matter experts to ensure data quality and reproducibility
• Collaboration & Laboratory Support
• Collaborate with chemists, automation scientists, and analytical experts across functions
• Participate in data reviews, troubleshooting discussions, and continuous process improvement efforts
• Support general laboratory operations, including inventory management, equipment upkeep, and lab organization

• BS or MS in Chemistry, Chemical Engineering, Pharmaceutical Sciences, or a related field
• 1-5 years of relevant pharmaceutical, biotech, or chemical research experience
• Strong attention to detail and data integrity
• Effective written and verbal communication skills
• Ability to work independently and collaboratively in a fast-paced environment

• Experience with laboratory automation and robotic systems
• Familiarity with air-free techniques and glovebox operations
• Working knowledge of chromatographic and analytical methods
• Proficiency with laboratory software, ELNs, and data analysis tools

SGA is a technology and resource solutions provider driven to stand out. We are a women-owned business. Our mission: to solve big IT problems with a more personal, boutique approach. Each year, we match consultants like you to more than 1,000 engagements. When we say let’s work better together, we mean it. You’ll join a diverse team built on these core values: customer service, employee development, and quality and integrity in everything we do.

Be yourself, love what you do and find your passion at work.

SGA is an Equal Opportunity Employer and does not discriminate on the basis of Race, Color, Sex, Sexual Orientation, Gender Identity, Religion, National Origin, Disability, Veteran Status, Age, Marital Status, Pregnancy, Genetic Information, or Other Legally Protected Status. We are committed to providing access, equal opportunity, and reasonable accommodation for individuals with disabilities in employment, and our services, programs, and activities.

Please visit our company to request an accommodation or assistance regarding our policy.