Associate Director​/Director, Program Management

About The Company

Marea Therapeutics is a clinical-stage biotechnology company based in South San Francisco with a growing pipeline of first-in-class therapies to address genetically validated cardioendocrine disease targets. Our therapies have the potential to complement existing therapies and serve as transformative treatment options for significant patient populations living with cardioendocrine diseases.

Incubated by Third Rock Ventures
, Marea completed a Series B financing in June 2024 and is well funded by a syndicate of leading life science investors including Sofinnova, Forbion, Xontogeny/ Perceptive Advisors, venBio, Omega Funds, Surveyor, Alpha Wave and Third Rock Ventures. The company’s lead program, MAR
001, is a monoclonal antibody targeting ANGPTL4, a genetically validated target with potential to address the subset of patients at the highest risk of adverse cardiovascular events, despite current standard of care therapies. MAR
001 is rapidly progressing through Phase 2b clinical development. Our second clinical asset, MAR
002, is a monoclonal antibody targeting excess growth hormone produced by the pituitary gland in the rare hormonal disorder, acromegaly. MAR
002 has potential to become best-in-disease and is rapidly progressing through Phase 1 clinical development. We also have a third asset that is rapidly advancing through research discovery, with DC nomination expected next year.

At Marea
, we believe in the power of collaboration and the importance of leading by example. We are a tight-knit team that values the contributions of every member, from interns to senior leaders. Our environment is dynamic, with each day presenting new challenges and opportunities for growth. Every role is “Hands-On”, and the successful candidate will be able to work alongside team members, regardless of level, to understand challenges and drive results.

The Associate Director/Director, Program Management will have both early and late phase pharmaceutical program management experience that includes knowledge of drug development processes and interdependencies of key functions including research, translational medicine, clinical, regulatory, and CMC.

The successful candidate should have strong project management skills, have the highest levels of scientific and ethical integrity, be self-motivated, and enjoy working in a dynamic, fast-paced biotechnology environment to support the development of transformational therapies for cardiometabolic diseases.

This is an full-time, San Francisco based position with the expectation of working onsite at least three days per week. The level of the role will be commensurate with the chosen applicant’s background and experience.

Cross-Functional Program Team and Sub-teams

• Partner with program team leader and other team members to develop the program vision, strategy, and goals/ objectives
• Lead and develop the cross-functional program plan including key assumptions, realistic but aggressive timeline, budget and resource planning, risk and mitigation assessment, and contingency planning
• Support and/or run effective program team (and sub-team) meetings, driving toward cross functional alignment and support for the execution of the program plan
• Partner closely with the program team leader (and research team leader for early development assets) to proactively identify and remove bottlenecks, surface and resolve issues, and help teams through technical and program challenges as they arise
• Coordinate and reconcile project team inputs to key project documents, e.g., presentations to leadership or the board of directors
• Promote curiosity, scientific rigor, and excellent problem-solving skills across a fast-paced, performance-driven environment

Program Tracking

• Develop, maintain and update the project plan through the course of the project, ensuring plan is phase appropriate, interdependency-linked, and aligned to program goals/strategic imperatives
• Manage and maintain complete and high-quality core program information and documents such as minutes, agendas, action items, development plans, integrated timelines,…