Scientist II, BioConjugation, Antibody Drug Conjugate

Scientist II, Bio Conjugation, Antibody Drug Conjugate

Astellas Pharma Inc. is a multinational pharmaceutical company committed to turning innovative science into medical solutions.

Our research division seeks a Scientist to work on bioconjugation for Antibody‑Drug Conjugates (ADCs), focusing on conjugation and purification of ADC to drive projects in SSF. The role collaborates closely with the Antibody Engineering group to advance our projects.

• Perform conjugation and purification to prepare ADCs to support research activities
• Design, optimize, and develop CMC‑friendly conjugation processes
• Lead the creation of optimal ADC clinical candidates by appropriate conjugation methods
• Manage CROs to perform above activities
• Actively participate in ADC projects, contributing to team decision‑making through creation of ADCs and the data generated
• Serve as an ADC Subject Matter Expert, offering appropriate advice and solutions
• Contribute to patents, publications, and technical reports

• PhD with 2+ years relevant laboratory experience in biologics research
• Extensive hands‑on experience with a wide range of conjugation chemistry, including lysine, cysteine, and enzymatic mediated methods
• Experience in analytical methods for protein characterization, ideally antibody‑related modalities
• Desire and ability to work in a cross‑functional, flexible, and team‑oriented environment
• CRO management experience
• Well‑balanced communication skills in own language and in English

• Experience in antibody‑related modality development especially in ADCs
• Experience supporting ADC development from discovery to early CMC development
• Experience in oncology research
• Experience in patent application
• Experience in collaborations with external research groups

This position is based in SSF and requires on‑site work.

$103,600–$162,800 (final compensation determined based on a variety of factors).

• Medical, Dental and Vision Insurance
• Generous Paid Time Off options, including vacation, sick time, and national holidays
• 401(k) match and annual company contribution
• Company‑paid life insurance
• Annual Corporate Bonus and Quarterly Sales Incentive for eligible positions
• Long Term Incentive Plan for eligible positions
• Company‑paid fleet vehicle for eligible positions
• Referral bonus program

Astellas is committed to equality of opportunity in all aspects of employment. EOE including disability/protected veterans.