Principal Scientist, Respiratory Diseases

Job Description

We are seeking an experienced scientist to join our team and drive innovation in respiratory medicine. The ideal candidate will bring deep expertise in respiratory drug development within a large pharmaceutical setting, with a strong track record of advancing programs from early discovery through clinical development. This role offers the opportunity to shape strategy, collaborate across disciplines, and deliver transformative therapies for patients with respiratory diseases.

• Lead or contribute to the discovery and development of novel respiratory medicines, from early research up to clinical development.
• Design and execute strategies for target identification, validation, and translational approaches in respiratory disease areas (e.g., COPD, asthma, pulmonary hypertension, NCFBE).
• Effectively manage and lead multiple projects, including experimental design, resource allocation, and timeline adherence, ensuring milestones are met and risks are proactively addressed.
• Collaborate cross‑functionally with medicinal chemistry, pharmacology, clinical, and regulatory teams to advance pipeline programs.
• Interpret complex data sets and provide scientific leadership to guide decision‑making.
• Stay current on emerging science, competitive landscape, and regulatory requirements in respiratory therapeutics.
• Manage and mentor junior scientists and foster a culture of innovation and collaboration.

• Ph.D., Pharm.
  
  D. or M.D. in biology, pharmacology or related discipline and eight (8) years of respiratory drug development experience.

• Proven track record of advancing respiratory programs from discovery through clinical phases.
• Strong understanding of respiratory disease biology, pharmacology, and translational science.
• Excellent communication and leadership skills; ability to influence across functions.

• Deep understanding of the disease biology and pathophysiology for one or more respiratory diseases.
• Experience with inhaled drug delivery systems and formulation development.
• Proficiency in pharmacology, PK/PD modeling, and translational science for respiratory indications.
• Familiarity with preclinical models of respiratory diseases and biomarker strategies.
• Knowledge of regulatory requirements and clinical development considerations for respiratory medicines.
• Ability to leverage data analytics and digital tools to support decision‑making.

• Disease Research
• Pharmacology
• Project Leadership
• Pulmonary Disease Research
• Pulmonology
• Respiratory Pharmacology
• Translational Research

• Expertise in inhalation technology
• Advanced data science capabilities
• Experience with biomarker development
• Regulatory liaison experience
• Proficiency in project management software
• Knowledge of global development strategies

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please  if you need an accommodation during the application or hiring process.

Effective September 5, 2023, employees in office‑based positions in the U.S. will be working a hybrid schedule of three total days on site per week (Monday‑Thursday, although specific days may vary by site), with Friday designated as a remote‑working day, unless business‑critical tasks require an on‑site presence. This model does not apply to field‑based, facility‑based, manufacturing‑based, or research‑based positions, positions covered by a collective‑bargaining agreement, or any position for which the company has determined that the job requirements cannot be reasonably met working remotely.

The salary range for this role is $ – $. An employee’s position within the range will be based on several factors including, but not limited to, relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs. The successful candidate will be eligible for an annual bonus and long‑term incentive, if applicable.

We offer a comprehensive package of benefits.…