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Senior Software Engineer

Job in Columbia, Lexington County, South Carolina, 29228, USA
Listing for: Datavant
Full Time position
Listed on 2026-01-24
Job specializations:
  • Software Development
    Senior Developer, Software Engineer, Cloud Engineer - Software
Job Description & How to Apply Below
Location: Columbia

Datavant is a data platform company and the world’s leader in health data exchange. Our vision is that every healthcare decision is powered by the right data, at the right time, in the right format.

Our platform is powered by the largest, most diverse health data network in the U.S., enabling data to be secure, accessible and usable to inform better health decisions. Datavant is trusted by the world’s leading life sciences companies, government agencies, and those who deliver and pay for care.

By joining Datavant today, you’re stepping onto a high-performing, values-driven team. Together, we’re rising to the challenge of tackling some of healthcare’s most complex problems with technology-forward solutions. Datavanters bring a diversity of professional, educational and life experiences to realize our bold vision for healthcare.

Senior Software Engineer

The Role

As a Senior Software Engineer, you will lead major initiatives that advance Datavant’s platform scalability and reliability. You’ll drive technical design, coach peers, and ensure system-wide quality and consistency.

What You’ll Do
  • Own architectural design and end-to-end delivery for key systems or migrations.
  • Partner with Product, Infrastructure, and Security teams to set technical direction.
  • Design scalable microservices and guide system decomposition initiatives.
  • Drive performance optimization, observability, and reliability improvements.
  • Mentor engineers at multiple levels and enhance team culture through best practices.
Tech Stack You’ll Work With

Senior engineers at this level are expected to leverage Datavant technologies effectively, demonstrate fluency across the stack, and use their architectural experience to design systems that are scalable, reliable, secure, and maintainable within Datavant’s platform. Your work will span Datavant’s core platform technologies, including:

  • Backend:
    Python, Go, Java; microservices; REST and GraphQL
  • Frontend:
    Type Script, React, Next.js
  • Infrastructure & Cloud: AWS (EC2, S3, IAM, Lambda), Docker, Kubernetes;
    IaC tools
  • Data:
    Snowflake, Spark, SQL; S3 for raw data
  • ETL & Pipelines:
    Airflow/Glue
  • Streaming:
    Kafka or Kinesis
  • Observability:
    Data Dog, Grafana, Cloud Watch
  • Security: OAuth2/SAML, encryption, tokenization, zero-trust architecture
What You Bring
  • 6+ years of professional experience developing and scaling distributed systems.
  • Deep expertise in system design, cloud-native architectures, and backend frameworks.
  • Proven record of leading major technical projects from inception to launch.
  • Strong collaboration with cross-functional teams (Product, Design, Infrastructure, Security).
  • Commitment to data integrity, privacy, and operational excellence.
Leadership Qualities & Mindset

Provides architectural leadership and technical clarity. Identify systemic issues and drive cross-team solutions.

  • Inspire confidence through technical expertise and build talent through thoughtful mentorship.
  • Balance innovation with pragmatic execution and long-term maintainability.
  • Act with humility, integrity, and focus on team success.
  • Drive alignment between engineering goals and business outcomes.
Core Value Expectations
  • Earn trust through high-quality architectural decisions and transparent leadership.
  • Obses over customers by prioritizing reliable, secure, scalable systems.
  • Prioritize growth over comfort by tackling complex, ambiguous technical challenges.
  • Win as a team by facilitating alignment and resolving cross-team challenges.
  • Rise to the challenge by owning key initiatives and elevating organizational excellence.
Why This Role Matters

As a Senior Software Enginer, you ensure the engineering organization’s systems are resilient, maintainable, and aligned with Datavant’s mission to securely connect healthcare data. You play a central role in advancing architecture and engineering culture.

We are committed to building a diverse team of Datavanters who are all responsible for stewarding a high-performance culture in which all Datavanters belong and thrive. We are proud to be an Equal Employment Opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, sex, sexual orientation, gender…

Position Requirements
10+ Years work experience
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