Research Associate - Synaptic dysfunction in neurodegeneration Job Sheffield area,England UK,Research/Development

The University of Sheffield provided pay range

This range is provided by The University of Sheffield. Your actual pay will be based on your skills and experience — talk with your recruiter to learn more.

Base pay range

Salary: £38,784.

Benefits

We offer a highly competitive annual leave entitlement (with the ability to purchase more), a generous pensions scheme, flexible working opportunities, a commitment to your development and wellbeing, a wide range of retail discounts, and much more.

Overview

Applications are invited for a postdoctoral research associate (PDRA) to join a collaborative research programme investigating the role of synaptic dysfunction and impaired neurotransmission in amyotrophic lateral sclerosis and frontotemporal dementia (ALS/FTD).

You will work within a team of two PDRAs and two senior research technicians under a 5‑year MRC‑funded collaborative research programme.

In this post you will lead the maintenance of curated iPSCs and the generation of iPSC‑derived neuronal cultures in which synaptic function will be examined using state‑of‑the‑art electrophysiological and microscopy‑based assays.

Candidates are strongly encouraged to contact Prof Kurt De Vos () and Dr Matthew Livesey () to discuss the project prior to application.

Main Duties And Responsibilities

Undertake research in line with project requirements.
Set‑up and run experiments in relation to the project in consultation with the PIs.
Manage data collection, analysis and storage on a day‑to‑day basis.
Work independently and as part of a team to deliver the research objectives in line with the project outline.
Direct the work of supporting technicians.
Liaise closely with other academics, advisers and administrators relevant to the study.
Take a lead role in the analysis, interpretation and writing up of data.
Read and review literature as appropriate.
Assist in the writing of the project reports and publications.
Contribute to conference presentations, research advisory group meetings.
Attend and contribute to project/lab meetings and research advisory group meetings.
Support project reporting requirements, including research project progress reports and finance management and reporting.
Contribute to the supervision and support of PhD students and MSc students working in the lab.
Carry out other duties, commensurate with the grade and remit of the post.

Person Specification

Our diverse community of staff and students recognises the unique abilities, backgrounds, and beliefs of all. We foster a culture where everyone feels they belong and is respected. Even if your past experience doesn't match perfectly with this role's criteria, your contribution is valuable, and we encourage you to apply. Please ensure that you reference the application criteria in the application statement when you apply.

Criteria

Essential or Desirable

Stage(s) assessed at:

A PhD in neuroscience, molecular/cell biology or a related discipline (applicants near completion of their PhD are welcome to apply).

Essential - Application

Experience working with human in vitro iPSC‑based models (iPSC maintenance, deriving defined cell types from iPSCs).

Essential - Application and Interview

Demonstrable experience in molecular, biochemistry and cell biology.

Essential - Application and Interview

Demonstrable experience in synaptic biology.