Assistant Investigator - Proteomics at Allen Institute Seattle, WA

Assistant Investigator, Proteomics – Allen Institute for Brain Science

mission of the Allen
Institute is to understand the principles that govern life and to advance health. Our creative and multi-dimensional teams focus on answering some of the biggest questions in bioscience. We accelerate foundational research, catalyze bold ideas, develop tools and models, and openly share our science to make a broad, transformational impact on the world.

The mission of the Allen Institute for Brain Science is to accelerate the understanding of how the human brain works in health and disease. Using a big science approach, we generate useful public resources, drive technological and analytical advances, and discover fundamental brain properties. Built on the foundational knowledge of brain cell types, the mission of the Allen Institute for Brain Science is to conduct a series of large-scale projects designed to create “CAP” (Complete, Accurate, Permanent) datasets and experimental tools;

gain fundamental knowledge in the development, evolution, connectivity and function of brain cell types; move towards a better understanding of mammalian brain function in healthy and diseased conditions; and disseminate the data, knowledge and tools broadly with the community, to accelerate research across the neuroscience field.

We seek an exceptional individual who will work with a team and will report to the Executive Vice President and Director of the Allen Institute for Brain Science. This individual will lead efforts in the Proteomics Initiative on novel affinity reagents development, and/or characterization of cell-type specific protein composition and subcellular localization. The proteomic work will provide a critical bridge between the genomic/transcriptomic profiles and the structure/function of brain cell types, leading to both novel insights and foundational resources about the molecular underpinnings of brain circuit function.

The candidate should have an exceptionally strong background in proteomics or protein science, preferably in the context of neuroscience. This person will have an excellent track record of publications and experience in applying for and acquiring funding to support scientific work. The ideal candidate will excel at leading and driving successful projects with internal and external scientific and technological collaborators. And they will fully embrace Allen Institute’s big science, team science, and open science approach.

At the Allen Institute, we believe that science is for everyone – and should be open to everyone. We are dedicated to combating biases and reducing barriers to STEM careers more broadly.

We also believe that science is better when it includes different perspectives and voices. We strive to make the Allen Institute a place where everyone feels like they belong and are empowered to do their best work in a supportive environment.

We are an equal-opportunity employer and strongly encourage people from all backgrounds to apply for our open positions.

• Lead the development and implementation of high-throughput screening and validation of affinity reagents for proteins of interest in the mouse and human brain
• Lead and/or collaborate with other teams to develop multiplexed protein detection approaches
• Lead and/or collaborate with other teams to develop proximity labeling, mass spectrometry, or imaging approaches to profile proteins in specific cell types and subcellular compartments
• Work collaboratively with other Institute teams to build pipelines and scale up proteomic data collection and analysis
• Present a periodic summary of progress to internal and external research community
• Publish and present findings in peer-reviewed journals and scientific meetings
• Apply for grants as a Principal Investigator

Note:

Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. This description reflects management’s assignment of essential functions; it does not proscribe or restrict the tasks that may be assigned.

• Ph.D. in Neuroscience, Biochemistry, Molecular Biology, or related field with an…