Senior Scientist- SBX Molecular Engineering

Senior Scientist- SBX Molecular Engineering

Join to apply for the Senior Scientist- SBX Molecular Engineering role at Roche
.

We advance science so that we all have more time with the people we love. Roche Diagnostics acquired Stratos Genomics in 2020 for its unique chemistry that advances DNA sequencing by nanopore, Sequencing by Expansion (SBX™). You will engineer and synthesize the molecular building blocks for our novel technology, translating DNA sequences into a simple to measure surrogate, the Xpandomer, which significantly improves the accuracy and throughput of nanopore sequencing.

• Research, design and execute innovative and well-controlled experiments, with high attention to detail
• Lead, mentor and drive cross functional teams
• Identify and troubleshoot problems in creative ways
• Contribute to the definition and timely achievement of project goals
• Develop SOPs to aid in the production of reagents and starting materials
• Participate in the production of reagents and starting materials
• Perform data analysis and protocol development
• Maintain accurate, detailed and reliable laboratory records
• Present findings at group or departmental meetings
• Maintain the lab’s cleanliness and organization
• Develop and propose improved processes to fulfill the above functions

• You have 6 years of laboratory experience in advanced nucleotide/heterocyclic chemistry, phosphorus chemistry and/or complex/multi-step organic synthesis
• You have a Bachelor’s degree in Organic Synthesis, Chemistry, Chemical Engineering, Biochemistry or a related field and 8 years of experience
• You have a Master’s degree in Organic Synthesis, Chemistry, Chemical Engineering, Biochemistry or a related field and 7 years of experience
• You have a PhD in Organic Synthesis, Chemistry, Chemical Engineering, Biochemistry or a related field and 4 years of experience
• Ideally, you will have:
• Demonstrated ability to understand and develop chemistry for:
• Nucleotides
• Phosphoramidites
• Heterocycles
• Amino Acids
• Bio-conjugations
• Mature understanding of how to work with chemical and biochemical samples, including sample handling, reactivity, purification and storage
• Technical background in next-generation DNA sequencing
• Experience with HPLC, MS, NMR, automated DNA synthesizers, inert atmosphere chambers, and manual pipetting

Please include a cover letter outlining why you want to work with us, your specific interest SBX technology and how you would contribute. This is important.

Relocation benefits are available for this posting.
Expected salary range for this position based on the primary location of Seattle, WA is $104,400 - $193,800. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and company performance.

Roche is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form for accommodations for applicants. Roche is an equal opportunity employer and strictly prohibits unlawful discrimination based upon an individual's race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, mental/physical disability, medical condition, marital status, veteran status, or any other characteristic protected by law.