Senior Program Officer, TB​/HIV Diagnostics Research & Development

** The Foundation
**** The Team
** Our Global Health (GH) division harnesses advances in science and technology to save lives in developing countries. We focus on the health problems that have a major impact in developing countries but get too little attention and funding. Where tools exist, we support sustainable ways to improve their delivery. Where they don’t, we invest in research and development of new interventions, such as vaccines, drugs, and diagnostics.

Our work in infectious diseases focuses on strategies to fight and prevent HIV/AIDS, malaria, tuberculosis (TB), neglected tropical diseases, enteric and diarrheal diseases, pneumonia and maternal, newborn and child health.
Our TB and HIV work is combined under a joint TB/HIV Program Strategy Team (PST) which focuses on research, development and delivery of new products and tools.
The goal of the tuberculosis (TB) Program Strategy is to accelerate the reduction in TB incidence globally through innovative discovery and development of new tools and approaches. The TB Program Strategy Team (PST) is responsible for R&D investments targeting more effective TB interventions including vaccines, diagnostics, and drugs. Current TB drug regimens are too long and complicated by drug resistance. The aim of the TB Drug Initiative is to deliver simpler, safer, markedly shorter pan-TB drug regimens leading to improved outcomes and lower incidence.

The TB Drug Initiative is responsible for setting strategy and managing an end-to-end drug portfolio, collaborating with internal and external partners, and overseeing product development from discovery to the introduction of new treatment regimens in Global Health markets.
The HIV team’s strategic vision is to accelerate the reduction in the incidence of HIV infection in high-burden geographies and populations, with a focus on the development of new prevention and treatment interventions, including long-acting drugs, vaccines and biologics, and to enable their effective use.
Accessible, low-cost, high-quality diagnostics are essential for early TB detection and for the success of any improved TB treatment regimen. The TB Diagnostics R&D portfolio focuses on near-point-of-care (nPOC) tests, distributable PCR kits, and affordable screening tools to expand testing and enable same-visit treatment initiation. HIV Diagnostics are an integral part of our planning for the effective introduction of novel long-acting prevention and treatment regimens.

We work in close partnership with the Enterics, Diagnostics, Genomics & Epidemiology (EDGE) and TB/HIV Delivery teams to define and manage a research and development portfolio of TB diagnostics and devices.
** Final date to receive applications:
Friday, February 13, 2026
**** Your Role
** You will be primarily responsible for informing and advancing the TB Diagnostics strategy through the shaping and management of a portfolio of high-impact investments aimed at accelerating the development, and validation of novel TB diagnostics for use in low- and middle-income countries (LMICs). You will work in close partnership with the EDGE (Enterics, Diagnostics, Genomics & Surveillance) and TB Delivery teams to guide scientific, technical, and partnership aspects of the diagnostics development pipeline and ensure alignment with the foundation’s TB diagnostics introduction goals.

You will also collaborate with the HIV team to define potential high value HIV diagnostics investments designed to advance the foundation’s HIV product introduction priorities. Together the role includes contributing to strategy formulation, managing complex grants and contracts, engaging with a diverse set of partners, and staying at the forefront of innovation and trends in diagnostics technologies. You will report to the Deputy Director of TB Drugs & Diagnostics.
** What You’ll Do**
* ** Lead and manage a strategic diagnostics R&D investment portfolio**, applying scientific, technical, and business expertise to identify, assess, fund, and oversee grants and contracts across discovery, technology validation, clinical evaluation, and implementation readiness.
* ** Provide strategic and technical leadership in diagnostics product development**, including risk-based decision-making, iterative milestone planning, and expert guidance to product developers, PDPs, academic groups, and implementing partners.
* ** Drive the creation and refinement of target product profiles (TPPs), use cases, and value propositions
** for TB/HIV diagnostics across diverse settings and populations, ensuring alignment with broader TB and HIV treatment and prevention strategies.
* ** Shape and implement program strategy
** by partnering with team leadership and contributing to the cross-functional TB/HIV Diagnostics R&D Initiative, including goal setting, investment planning, and execution.
* ** Review and recommend funding opportunities**, including evaluation of letters of inquiry and proposals, and prepare clear, concise analyses and funding…