Senior Scientist - Seattle, WA

Senior Scientist - Seattle, WA

Vet Jobs is seeking an experienced senior scientist for the Cell Therapy Analytical Development (CTAD) department. The role is on‑site in Seattle, WA.

This position is available to veterans, transitioning military, National Guard, Reserve members, military spouses, wounded warriors, and their caregivers, unless otherwise stated. The role requires on‑site presence.

As a Senior Scientist, you will develop and troubleshoot LC‑MS assays to advance gene‑edited cell therapy development. You will independently develop and execute LC‑MS methods for oligonucleotide process development and for the characterization of autologous and allogenic cell therapy products in clinical trials, designing experiments with minimal supervision.

• Design, develop, optimize, and standardize robust physiochemical methods—LC, LC‑MS, CE, SEC/AEX‑MALS, preparative LC‑MS—for sample quality control and characterization of oligonucleotides and proteins.
• Maintain and troubleshoot instrumentation (UPLC, LC‑MS, CE, MALS) to ensure high performance, reliability, and minimal downtime.
• Maintain meticulous laboratory notebooks and manage routine sample analysis requests.
• Present scientific results and observations to colleagues, management, and external partners.
• Author, review, and approve technical documents, including methods, protocols, reports, and regulatory submissions.
• Apply good knowledge of cGMP and ICH/FDA/EMEA guidance.
• Complete regulatory, site, and department training requirements on a timely basis.

• Bachelor’s degree required;
  PhD preferred with 3+ years’ experience or Bachelor’s with 10+ years in pharmaceutical research, development, or related industry.
• Expertise in HPLC and LC‑MS instrumentation, including setup, operation, troubleshooting, maintenance, and method development.
• Proficiency with software such as Empower, Xcalibur, Chromeleon, Biopharma Finder, Protein Metrics, etc.
• Strong background in separations sciences: SEC, RP, IEX, HILIC, CE.
• Expertise in LC‑MS and LC‑MS/MS methods for large biomolecules (e.g., mAb, ADC, proteins) and for nucleic acid‑based compounds.
• Experience developing LC‑MS/MS analytical methods for nucleic acid‑based modalities (oligonucleotides, RNA, DNA).
• Ability to work collaboratively in a team and adapt to frequently changing priorities.
• Strong written and oral communication skills.
• Experience in a cGMP environment is preferred.

Seattle, WA: $128,890 – $156,179 annually. Additional incentive cash and stock opportunities may be available based on eligibility.