Senior Scientist, Biology

Overview

Dovetail Therapeutics is a Seattle biopharmaceutical company founded in 2023 by the world’s leading healthcare venture capital firm Orbi Med. Dovetail is committed to developing novel biotherapeutics that will meaningfully improve the lives of patients. The company has established a transformative, proprietary platform and a robust, expanding pipeline, with its lead drug candidate entering the clinic this year.

• Design and execute functional characterization strategies for research programs across a variety of disease areas, with focus on human biology.
• Lead day-to-day operations of antibody-based drug discovery programs from initiation through screening to lead selection.
• Independently develop, perform, and troubleshoot in vitro assays. Analyze and present data to project teams and leadership. Define next steps.
• Work with internal cross-functional teams to advance novel biotherapeutic programs.
• Compile data packages for DC selection, write sections of regulatory documents, prepare materials for external interactions and BOD meetings.
• Mentor and develop junior staff in laboratory work.
• Apply innovative approaches and stay current with advances in biologics, competitive landscape and clinical trial learnings to strengthen existing programs and pipeline opportunities.

• Ph.D. in immunology, cell biology, pharmacology or related discipline and minimum of 1-3 years of relevant industry experience.
• Proven experience in leadership of preclinical antibody programs including project initiation and strategy and day-to-day operations. Demonstration of excellence through project progression and milestone achievements.
• Robust understanding of selection and characterization of biologic molecules for lead selection. Experience in writing study reports, IND sections and other regulatory documents.
• Extensive hands-on expertise in cell-based methodologies, including but not limited to cell-based functional assays (both cell lines and primary cells), ELISA, MSD, flow cytometry and qRT-PCR.
• Experience in interaction with external stakeholders, for example transferring protocols to CROs, setting up and managing external collaborations.
• Self-driven and proactive, with the ability to lead projects, manage multiple priorities, and adapt to evolving objectives in a fast-paced environment.
• Excellent organizational and communication skills with attention to detail.

We foster a culture of collaboration and innovation, with each team member playing a critical role in shaping our success. Dovetail offers a competitive total compensation and benefits package. Benefits include medical, dental and vision coverage, paid parking or transit, a 401(k) plan, and paid time off, among other components. Dovetail Therapeutics is located at 1616 Eastlake Avenue East, in the vibrant South Lake Union neighborhood of Seattle.