Senior Scientist - Animal Health

** Job Description
***
* Job Title:

Senior Scientist – Downstream Process Development
***
* Position Summary:

** We are seeking an experienced and highly skilled Senior Scientist to join our Monoclonal Antibody Research Group. The successful candidate will have a deep understanding of downstream process unit operations and hands-on experience with chromatography systems such as AKTA. This role requires a PhD or 5+ years of industry experience in the relevant field, strong problem-solving skills, and the ability to work with external partners..
*
* Key Responsibilities:

*** Lead the development and optimization of the downstream processes for the purification of monoclonal antibodies or related antibody products.
* Design and execute experiments to evaluate and improve process performance.
* Utilize chromatography systems (e.g., AKTA and Unicorn software) and other purification techniques to achieve the desired purity and yield.
* Develop and implement robust and scalable processes for technology transfer to external partners or internal manufacturing.
* Process and produce materials at bench or pilot scale to support pre-clinical and clinical studies.
* Collaborate with cross-functional teams, including cell line development, upstream, analytical, formulation, clinical, regulatory, sourcing and manufacturing.
* Engage with external partners and stakeholders to ensure alignment and successful project execution and deliverables.
* Conduct root cause analysis and assay optimization individually or in a group setting
* Manage and leverage the resources within the team and department to ensure on-time delivery of project timeline and milestones.
* Stay informed of external advances and technologies for continuous improvement of the process and expansion of capabilities.
* Provide coaching or assistance to other team members.
*
* Qualifications:

***
* Education:

** Master's degree in Biochemistry, Biotechnology, Chemical Engineering, or a related field, with minimum 5 years of industry experience in downstream process development.....OR PhD in Biochemistry, Biotechnology, Chemical Engineering, or a related field
** Required

Experience and Skills:

*** Deep understanding of each unit operation in the downstream process, including chromatography, filtration, and ultrafiltration/diafiltration.
* Broad knowledge and understanding of the interaction of the downstream process with product quality including the purity, impurity and potency.
* Hands-on experience with AKTA or similar chromatography systems.
* Strong problem-solving skills and the ability to troubleshoot and optimize processes.
* Excellent communication and teamwork abilities.
* Proven track record of successful process development and technology transfer in the industry setting.
** Preferred

Experience and Skills:

*** Knowledge and experience with different recombinant protein expression and purification system at industry scale.
* Knowledge and experience in recombinant protein develop ability and manufacturability assessment.
* Knowledge in process scale up, scale down, process characterization, qualification and validation.
* Knowledge and experience using DOE approach in process development.
* Familiarity with Good Manufacturing Practices (GMP) and regulatory guidelines (e.g., FDA, EMA).
* Experience working with external partners and managing collaborative projects.
*
* Required Skills:

** Adaptability, Assay Development, Biochemical Analysis, Biochemical Assays, Biotechnology, Chemical Engineering, Chromatography, Detail-Oriented, Drug Target Identification, Flow Cytometry, Good Manufacturing Practices (GMP), Immunoassays, Immunochemistry, Immunology, Molecular Biology, Monoclonal Antibodies, Personal Initiative, Polyclonal Antibody Production, Production Process Development, Protein Expression, Protein Purifications, Teamwork
** Preferred

Skills:

** Current Employees apply

Current Contingent Workers apply
** US and Puerto Rico Residents Only:
** Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please  if you need an accommodation during the application or hiring process.

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