Principal Mechanical Engineer II, Early Research and Development
Listed on 2026-03-10
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Engineering
Mechanical Engineer
Position: Principal Mechanical Engineer II, Early Research and Development,
Req#: ROCGJP
Location: Santa Clara, CA (100% onsite only)
Duration: 6+ Months Contract with potential to extend
Interview Process: 1. phone 2. In-person Interviews and Presentation (Candidate would need to do a bio presentation of skill sets etc.)
A cover letter is required for this application. Please outline your relevant experience and explain why you are interested in this role and our company.
We are ideally looking for mechanical engineering candidates from the Life Science/Biotech space having experience with at least 2 areas of expertise: fluidics, pneumatics, electromechanical/automation, thermal.
Job Description:
A healthier future. It's what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love.
We are working to make next-generation sequencing simple and accessible enough for routine use. By accelerating clinical research, streamlining workflows, and expanding assay menus, we are broadening access to genomic data and lowering barriers to adoption. From robust sample isolation and preparation tools to Client sequencing technology and advanced bioinformatics, we are developing differentiated, highly integrated end-to-end solutions for next-generation sequencing, resulting in a sample in, result out workflow.
Our Systems Technology Group, a part of the client's Sequencing Solutions, is focused on creating and advancing technologies to significantly enhance DNA sequencing workflows. We are seeking a Principal Mechanical Engineer to lead the mechanical design, development, characterization, and integration of cutting-edge sequencing systems.
This is a hands-on role for a multidisciplinary expert focused on solving the core mechanical challenges at the heart of our next-generation platforms. You will be responsible for concepting, designing, building, and testing Client electro-mechanical, pneumatic, thermal, and fluidic solutions that ensure the ultimate performance, reliability, and longevity of our systems.
The Principal Mechanical Engineer will play a vital role in driving innovation for our next-generation instrumentation. We are looking for someone who exhibits a high degree of motivation, independence, and resourcefulness to help us develop solutions to Client DNA Sequencing and automation challenges in a fast-paced and collaborative environment.
Education and Experience Requirements :
- You have a PhD in Mechanical Engineering, Bioengineering, or a related discipline with at least 3 years of relevant industry experience; or a Master's degree in Mechanical Engineering, Bioengineering, or a related discipline with at least 4 years of relevant industry experience; or a Bachelor's degree in Mechanical Engineering, Bioengineering, or a related discipline with at least 7 years+ of relevant industry experience.
- You have demonstrated deep, hands-on expertise in the design, development, and testing of complex mechanical, electro-mechanical, and pneumatic systems, preferably for life science or diagnostic instrumentation.
- You have demonstrated hands-on expertise in thermal management and the design of precision temperature control systems.
- You have experience developing fluidics systems and their interfaces including pumps, valves, tubing, sensors, and material selection.
- You possess strong proficiency in 3D CAD software (e.g., Solid Works) for detailed design and the creation of manufacturing drawings.
- You have expertise in designing components for a variety of manufacturing processes (e.g., machining, injection molding, 3D printing).
- You are a creative and resourceful problem-solver, with the ability to troubleshoot complex issues at the interface of hardware, software, and chemistry.
- You are proficient with common machine shop tools, as well as test and measurement equipment; proficient with rapid prototyping technology such as 3D printers, laser cutters, CNC mills/lathes, etc, and
- You have a demonstrated level of proficiency with Python, LabVIEW, or similar tools for device control and data acquisition.
Preferred:
- You have demonstrated the ability to lead technical projects and mentor junior engineers, providing clear guidance and delegating tasks to achieve project goals.
- You have experience using simulation tools (CFD, FEA) to guide design decisions.
- You have previously worked on the development of next-generation sequencing (NGS) or other genomics instrumentation.
- You have experience working in a regulated product development environment
- You have demonstrated strong interpersonal and communication skills with the ability to communicate technical knowledge in a clear and understandable manner, especially to non-experts; you excel at problem-solving skills and the ability to work under ambiguous situations.
- You have excellent organizational skills, including the ability to efficiently…
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