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Scientist; Mass Spectrometry

Job in San Juan Capistrano, Orange County, California, 92675, USA
Listing for: Quest Diagnostics
Full Time position
Listed on 2026-02-07
Job specializations:
  • Healthcare
    Clinical Research
  • Research/Development
    Research Scientist, Clinical Research
Job Description & How to Apply Below
Position: Scientist (Mass Spectrometry)

Overview

At Quest Diagnostics, our Scientists will be responsible for supporting the development, validation and transfer of both FDA and non-FDA analytical methods for the quantification of various analytes (i.e. small molecules) by GC-MS, LC-MS/MS. This professional will plan, prepare, conduct and record complex bench level chemical/biochemical experiments, reports and analysis of results. Activities may be focused on individual projects or assignments as a member of a project team which may include project leadership duties.

This person will work within the R&D Mass Spectrometry group developing clinical mass spec-based assays for diagnostics testing.

Responsibilities
  • Plans, conducts, performs and executes laboratory experiments for GC-MS, LC-MS/MS for both defined and novel protocols. Reports status of assigned projects by preparing detailed reports and documentation that critically interprets and summarizes results from complex experiments within a specific project or technology area.
  • Effectively utilizes and applies advanced methods by maintaining knowledge of technological developments that may assist in the completion of an assignment or lead to novel ideas by reading current literature and attending scientific meetings and training.
  • The individual will be expected to generate, compile, analyze and evaluate analytical data for technical reports including regulatory submissions, SOPs, validation reports. The candidate will be encouraged to submit abstracts for posters/presentations at scientific meetings.
  • Identifies problems, investigates alternatives and recommends possible courses of action.
  • Able to troubleshoot and resolve technical difficulties
  • Ability to perform and prioritize multiple tasks/projects
  • Other responsibilities include working with infectious materials, supporting and complying with the company hazard waste handling practices.
Qualifications
  • Experience or strong understanding of laboratory techniques including but not limited to: sample preparation & extraction (e.g. precipitation, solid phase extraction) analyte quantitation using isotopically-labeled internal standards, or familiarity with HPLC and mass spectrometry.
  • Prior experience in enzymology/enzyme assay development, compound optimization, operation and troubleshooting of various GC-MS, LC-MS/MS platforms is a plus.
  • Self-starter with ability to perform experimental work independently and in collaboration with others; proficient with common data processing software (Excel, R, etc.) and ability to present data clearly.
Education
  • BS with 2-3 years of related experience
  • MS with 1 year of related experience
  • PhD and one year Post Doc experience, or related
  • Experience working in a biochemical genetics and chemistry laboratory setting is preferred.
About The Team

Quest Diagnostics honors our service members and encourages veterans to apply. Equal Opportunity

Employer:

Race/Color/Sex/Sexual Orientation/Gender Identity/Religion/National Origin/Disability/Vets or any other legally protected status.

While we appreciate and value our staffing partners, we do not accept unsolicited resumes from agencies. Quest will not be responsible for paying agency fees for any individual as to whom an agency has sent an unsolicited resume.

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