Senior Director, Commercial Supply Chain

Senior Director, Commercial Supply Chain

Vir Biotechnology is a clinical‑stage biopharmaceutical company focused on powering the immune system to transform lives by discovering and developing medicines for serious infectious diseases and cancer. Its clinical‑stage portfolio includes programs for chronic hepatitis delta and multiple dual‑masked T‑cell engagers across validated targets in solid tumor indications. Vir Biotechnology also has a preclinical portfolio of programs across a range of infectious diseases and oncologic malignancies.

We believe the success of our colleagues drives the success of our mission. We are committed to creating a company where everyone feels supported and encouraged to give their best.

Vir Biotechnology is looking for a Sr. Director Commercial Supply Chain to lead the company's supply chain operations for the launch of our commercial Chronic Hepatitis Delta (CHD) Program and to ensure continuity and reliability of high‑quality product supply.

Reporting to the VP of Product Strategy, you will develop and execute the end‑to‑end supply chain and distribution strategy for our CHD commercial launch. This is a hands‑on, strategic role where you will design and implement supply chain planning, logistics, and distribution processes while leading cross‑functional teams and managing CMO/CDMO and 3PL partnerships.

You will collaborate closely with CMC, Commercial, Technical Operations, Procurement, Alliance Management, Legal, and Finance teams as well as our European commercialization partners to build a robust supply chain that delivers reliable, compliant product supply from manufacturing through patient delivery.

This role is located in our San Francisco headquarters with an expectation of 3 days per week on site.

• Develop and execute the supply chain commercialization strategy and operational plan to ensure successful product launch and ongoing supply continuity.
• Establish and manage Vir's third‑party logistics (3PL) network and distribution strategy (including specialty distributors and specialty pharmacies). Develop a modern and value‑maximizing distribution strategy for a combination product with both physician‑administered and at‑home administration presentations. Collaborate with European commercialization partners to align supply plans across Europe, Australia, and New Zealand markets.
• Design and implement end‑to‑end supply chain processes including Sales & Operations Planning (S&OP), demand planning, materials management, inventory optimization, and distribution logistics. Establish KPIs, governance processes, and analytical models to enable data‑driven decision‑making and risk mitigation.
• Lead supply/demand scenario planning and capacity analyses to support executive decision‑making on commercialization milestones and long‑term supply strategy.
• Lead cross‑functional teams across CMC, Commercial, Technical Operations, Quality, Regulatory, and Finance to ensure integrated launch execution and ongoing supply chain performance.

• Bachelor’s degree in engineering, science, or supply chain with 18+ years of pharmaceutical/biotechnology supply chain and operations experience. MBA or advanced degree preferred.
• Proven track record leading pharmaceutical product launches at a small or virtual biotechnology company, with demonstrated success building supply chain infrastructure and capabilities from scratch, including supply chain strategy, S&OP, demand planning, inventory optimization, and 3PL/distribution management.
• Deep understanding of cGMP manufacturing and GDP distribution requirements with experience implementing compliant supply chain processes and systems.
• Skilled at leading cross‑functional and matrixed teams in fast‑paced environments. Proven ability to influence executive decisions, build consensus, and drive results through collaboration.
• Experience managing CMOs/CDMOs, 3PL providers, and international commercialization partners, including contract negotiation and supplier performance management.
• Strong analytical capabilities with experience developing data‑driven models, scenario planning tools, and…