Manager, IT Quality & Compliance

• Pre-tax commuter benefits

When was the last time you achieved the impossible? If that thought feels overwhelming, you might want to pause here, but if it sparks excitement... read on

In 2015, we pioneered a “moneyball for biotech” approach, pooling projects and promising early‑stage research from academia together under one financial umbrella to reduce risk and unleash innovation. This model allows science and small teams of experts to lead the way. We build bridges to groundbreaking advancements in rare disease, and develop life‑changing medicines for patients with unmet needs as fast as humanly possible.

Together we define white space, push boundaries and empower people to solve problems. If you're someone who defies convention, join us and work alongside some of the most respected minds in the industry. Together, we'll ask "why not?" and help reengineer the future of biopharma.

The Manager, IT Quality & Compliance will report to the Associate Director, IT Quality and Compliance and will be responsible for supporting the execution and ongoing operation of Bridge Bio’s IT compliance programs. This role will focus primarily on SOX IT General Controls (ITGCs) and IT Application Controls (ITACs), with meaningful involvement in other technology and regulatory compliance areas such as GxP Computer System Validation and data privacy (e.g., GDPR).

As a key contributor within the Bridge Bio Information Technology organization, the IT Compliance Manager will partner closely with IT, Finance, Quality, and business stakeholders to ensure IT control requirements are well understood, consistently executed, and appropriately documented. The ideal candidate is detail‑oriented, proactive, and capable of managing multiple priorities in a fast‑paced and evolving environment.

• Support and manage the Company's IT SOX Audit program, including planning, execution, and monitoring of IT control activities under the director of IT Quality and Compliance Leadership
• Perform day-to‑day management of ITGC and ITAC activities, including evidence collection, control execution validation, and issue tracking
• Assist in identifying and assessing IT risks that impact the Company’s SOX control environment

• Serve as a key liaison with internal and external auditors for assigned IT compliance activities
• Coordinate and participate in audit walkthroughs, testing, and follow‑up requests
• Provide timely and accurate audit evidence and responses in collaboration with IT process owners

• Assist in the design, implementation, and maintenance of IT controls in alignment with SOX and regulatory requirements
• Evaluate control performance and identify gaps or inefficiencies
• Execute and support preparation of IT General Controls, IT Application Controls, and key reports

• Support IT risk assessments and help identify control deficiencies or emerging risks
• Perform root cause analysis for identified control issues
• Track remediation plans, validate corrective actions, and support closure of findings

• Support IT Change Management processes, including review of changes for compliance with established policies and controls
• Assist with user access reviews (UARs), including coordination, execution, and documentation

• Ensure accurate and timely documentation of IT control processes, including control narratives, test plans, and results
• Assist in preparing status updates and reports for management regarding IT compliance activities and remediation progress

• Identify opportunities to improve efficiency, consistency, and effectiveness of IT compliance processes
• Collaborate with IT teams and business partners to enhance control awareness and compliance maturity
• Support training and guidance efforts related to IT compliance requirements and best practices

• Assist with third‑party IT risk and control assessments as needed
• Support reviews of vendor controls and documentation related to compliance obligations