Software Engineer, Informatics

We are seeking a talented and motivated Software Engineer in our San Diego headquarters to join the tightly integrated technology and drug discovery operation at Iambic Therapeutics. You’ll work closely with scientists across disciplines to ensure experimental data from our laboratory—ranging from biochemical activity assays to pharmacokinetic measurements—is accurately processed, curated, and integrated into our data platform. Your key responsibilities include contributing to the development, testing, and release of software for our drug discovery platform.

• Work in a cross‑functional team that spans the full domain of drug discovery
• Support a software platform that supports the drug discovery Design‑Make‑Test‑Analyze (DMTA) process
• Develop and maintain data workflows to parse, validate, and upload experimental data (e.g., ADME, PK, biologic assay data) from lab‑generated files such as Excel, CSV, and instrument exports
• Collaborate with lab scientists to define and model new assays in our data systems, ensuring metadata and measurement structures align with scientific intent
• Ensure data integrity and consistency through automated validation, schema enforcement, and version‑controlled pipelines
• Implement and maintain Python software and APIs that streamline data ingestion, curation, and accessibility for downstream analysis
• Work with ML scientists, computational chemists, biologists, and data engineers to improve data readiness for model training and scientific insight
• Participate in code reviews
• Clearly communicate work in meetings and company demos at a level suited to the audience

• Minimum of 5 years of related experience with a bachelor's degree; or 3 years and a master's degree; or a PhD; or equivalent experience in Chemistry or Biology or a related field
• PhD in Chemistry, Biology or a related field preferred
• Strong software and technical skills
• Proficiency in Python and the scientific computing ecosystem (e.g., Pydantic, asyncio, FastAPI, etc.)
• Ability to communicate with ML engineers
• Demonstrated competence and rigor in software development

Iambic is a clinical‑stage life‑science and technology company developing novel medicines using its AI‑driven discovery and development platform. Based in San Diego and founded in 2020, Iambic has assembled a world‑class team that unites pioneering AI experts and experienced drug hunters. The Iambic platform has demonstrated delivery of new drug candidates to human clinical trials with unprecedented speed and across multiple target classes and mechanisms of action.

Iambic is advancing a pipeline of potential best‑in‑class and first‑in‑class clinical assets, both internally and in partnership, to address urgent unmet patient need. Learn more about the Iambic team, platform, pipeline, and partnerships .

MISSION & CORE VALUES

Our mission is to deliver better medicines through innovations in AI‑based discovery technologies. The culture and work at Iambic Therapeutics are profoundly strengthened by the diversity of our people and our differences in background, culture, national origin, religion, sexual orientation, and life experiences. We are committed to building an inclusive environment where a diverse group of talented humans work together to discover therapeutics and create technologies.

We offer industry‑leading competitive pay, company‑paid healthcare, flexible spending accounts, voluntary life insurance, 401(k) matching, and uncapped vacation. Our state‑of‑the‑art facility in San Diego includes an onsite gym, dining, and easy access to great places to live and play. Compensation Range: $129K - $162K.