Postdoctoral Research Scientist, Gene Therapy

Who We Are:

At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering for people with great needs.

Neurocrine Biosciences is a leading neuroscience-focused, biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs. We are dedicated to discovering and developing life-changing treatments for patients with under-addressed neurological, neuroendocrine and neuropsychiatric disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal hyperplasia, endometriosis and uterine fibroids, as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas.

For three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders because you deserve brave science. For more information, visit  and follow the company on Linked In, X and Facebook. (
* in collaboration with Abb Vie)

The Postdoctoral Scientist in Gene Therapy will participate in conducting preclinical stage Gene Therapy programs at Neurocrine using AAV vectors. Working with our Collaboration Partners and internal colleagues in Research, CMC, and Business Development, the individual will participate in work on new and existing programs.

• Initiate and conduct a novel Gene Therapy research project.
• Design and perform in vitro and in vivo studies in support of current and future Gene Therapy opportunities.
• Prepare data summaries and present results to peers and colleagues at Neurocrine.
• Be able to present data as appropriate at scientific meetings at the National and International level.
• Other tasks as assigned.

• Ph.D. degree in biology, life sciences or related discipline, with experience in the biotech/pharmaceutical industry OR with prior non-industry postdoc experience.
• Experience with the application of gene therapy methods to animal experimental disease models. This includes experience with viral (preferably AAV) and/or non-viral gene delivery for up regulation of gene expression, downregulation, genome-editing or delivery of genetic material via lipid nanoparticles.
• Knowledge about AAV vector design, capsid/cargo, serotypes, promoters, enhancers.
• Experience or exposure to neuro-endocrinology or metabolism research will be a plus.
• General knowledge about the function of the central and autonomic nervous systems and gastrointestinal system.
• Experience in advanced experimental technologies and their utilization in the drug discovery process.
• Experience with primary neurons and iPSC-derived neurons, and their use in assay development a plus.
• In vivo experience working with animal models of disease.
• Excellent critical analysis skills.
• Assimilates data and research findings outside of Neurocrine for application to new scientific projects.
• Maintains broad knowledge of scientific principles and theories and possesses intellectual mastery of one or more scientific areas.
• Advanced knowledge and demonstrated ability working with / recommending a variety of laboratory equipment/tools.
• Ability to work as part of teams.
• Excellent computer skills.
• Excellent communications, problem-solving, analytical thinking skills.
• Ability to meet multiple deadlines across a variety of projects/programs, with a high degree of accuracy and efficiency.

The annual base salary we reasonably expect to pay is $89,800.00-$. Individual pay decisions depend on various factors, such as primary work location, complexity and responsibility of role, job duties/requirements, and relevant experience and skills. In addition, this position offers an annual bonus with a target of 20% of the earned base salary and eligibility to participate in our equity based long term incentive program.

Benefits offered include a retirement savings plan (with company match), paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans.

Neurocrine Biosciences is an EEO/Disability/Vets employer.

We are committed to building a workplace of belonging, respect, and empowerment, and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don’t line up to exactly what we have outlined in the job description.