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Sr. Bioinformatics Scientist

Job in San Diego, San Diego County, California, 92101, USA
Listing for: Exact Sciences
Full Time position
Listed on 2026-01-24
Job specializations:
  • Research/Development
    Research Scientist, Data Scientist, Biotechnology
Job Description & How to Apply Below

Sr. Bioinformatics Scientist at Exact Sciences summary:

The Senior Bioinformatics Scientist leads complex research and development projects focused on cancer diagnostics, independently analyzing data, developing new methods, and providing technical guidance. This role involves collaboration with cross-functional teams, mentoring junior scientists, and utilizing high-performance computing environments for bioinformatics analyses. The position supports innovation and product development in the biotechnology and molecular diagnostics sector, requiring extensive expertise in bioinformatics, molecular biology, and computational methods.

Help us change lives

At Exact Sciences, we’re helping change how the world prevents, detects and guides treatment for cancer. We give patients and clinicians the clarity needed to make confident decisions when they matter most. Join our team to find a purpose-driven career, an inclusive culture, and robust benefits to support your life while you’re working to help others.

Position Overview

The Senior Bioinformatics Scientist, with input from senior scientists and leaders, works in collaboration with others on one or more projects which are complex in scope. The Senior Research Scientist participates in or leads planning of projects and analyses and is often the bioinformatics lead responsible for the successful execution of the project. This position involves independently making detailed observations, analyzing data, interpreting results, and providing insights into the next steps and direction of the project, as well as independently determining methods and procedures on new assignments or projects.

Working in a team setting, the Senior Bioinformatics Scientist will be involved in Research and Development projects serving as a technical lead and/or a subject matter expert in exploring and researching new technologies, providing ideas and concepts to improve or develop processes, and/or establish methods and processes for product development towards development of diagnostic assay products. The Senior Bioinformatics Scientist will mentor and provide technical guidance to junior scientists in project teams.

This position is onsite at our San Diego office.

Essential Duties

Include, but are not limited to, the following:

  • Conduct analyses within several product or technology areas and identify problems and discrepancies.
  • Independently develop, plan, and analyze results of bench level experiments within several product or technology areas; effectively present and clearly communicate findings at data meetings, group meetings and project team meetings.
  • Analyze research/experimental data, interpret the results, and provide insights into the next steps and the direction of the project.
  • Independently develop methods and procedures for new assignments/study/experiments.
  • Provide technical guidance to junior scientists in project teams.
  • Manage bench-generated data and bioinformatics outputs within high performance computing (HPC) or cloud computing environment.
  • Determine, utilize, and apply methods or technologies effectively and provide ideas for new techniques, when appropriate.
  • Maintain knowledge of technological industry developments that could assist in completion of an assignment or aid in the development of new processes or procedures.
  • Provide technical input and participate in decisions affecting project planning and experimental design.
  • Prepare and provide information and data for scientific abstracts/conferences/project meetings/publication.
  • Contribute to the intellectual property portfolio by implementing innovative and creative ideas to solve problems or improve on current methods.
  • Generate, document, and communicate development plans for critical aspects of a project.
  • Develop research plans and experimental outlines to write experimental protocols and perform laboratory experiments.
  • Prepare detailed technical procedures, protocols, and reports.
  • Evaluate impact of nonconforming data to product or process.
  • Identify and address trends in study data.
  • Prepare and approve written reports.
  • Lead identification of areas for process improvements.
  • Maintain lab notebook in a clear, complete, and consistent manner, following all legal, ISO, and QSR requirements.
  • Prepare reports and documentation providing highly technical analysis or summarization of experimental results, outcomes, next steps, and the future direction of the project to functional leader, technical teams/groups, or project teams.
  • Present experimental results and defend scientific ideas and findings at data meetings, group meetings, project team meetings and/or departmental meetings, lead meetings as subject matter expert.
  • Demonstrate technical proficiency, scientific creativity and rigor, collaboration with others, and independent thought and ability to provide insights and defend scientific ideas.
  • Work on problems of extremely complex scope in which analysis of data requires an evaluation of intangible variables.
  • Exercise independent judgment in…
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