Immune and Brain Function Research | Innovative Therapeutics Development | Machine Learning & AI

Overview

POSTDOCTORAL POSITION

Immune and Brain Function Research | Innovative Therapeutics Development | Machine Learning & AI Integration

University of California San Diego, La Jolla, California

Positions available immediately for highly motivated recent PhDs and/or MDs to join multidisciplinary teams conducting translational and basic science research.

Successful candidates will contribute to cutting-edge projects integrating machine learning and artificial intelligence approaches including:

• Single-cell genomics studies generating comprehensive cellular atlases of human and nonhuman primate brain regions, examining transcriptomic and epigenetic landscapes and their alterations by viruses and drugs, utilizing ML/AI for data integration and predictive modeling
• Design and evaluation of novel RNA vaccines and gene therapies employing AI-driven sequence optimization and immunogenicity prediction
• RNA biology mechanisms underlying immune functions and their modulation by RNA viruses and cancer, leveraging machine learning for RNA structure prediction and regulatory network analysis
• Epitranscriptomic regulation of cancer and host-pathogen interactions using AI-based pattern recognition and multi-omics data integration
• Development and application of human stem cell-derived 3D organoids and disease models with machine learning approaches for phenotype analysis and predictive modeling
• Structure-based drug design, synthesis, and targeted protein degradation strategies powered by AI-driven molecular modeling and generative chemistry

iPSC generation and differentiation, human brain and lung organoid models, CRISPR, RNAi, RNA/gene delivery systems, single-cell genomics (scRNA-seq, scATAC-seq), spatial transcriptomics, bioinformatics, machine learning/AI algorithms, deep learning frameworks, in vitro/in vivo models, computational drug design and synthesis, biochemical kinetics assays.

Strong training in biochemistry, bioinformatics, immunology, neuroscience, molecular/cell biology, virology, medicinal chemistry, chemical biology, computational biology, machine learning, artificial intelligence, or data science. Experience with ML/AI applications in biological research is highly desirable. Demonstrated publication record and ability to conduct independent research required.

Join a dynamic, collaborative research environment at UC San Diego featuring state-of-the-art instrumentation, advanced computational infrastructure for ML/AI applications, and cutting-edge facilities spanning the Biomedical Sciences Program, Bioinformatics and Systems Biology Program, Moores Cancer Center, Institute for Genomic Medicine, and Center for Drug Discovery Innovation.

Submit CV and contact information for three references to:
ranaoffice

Research program details:
(Use the "Apply for this Job" box below)..edu