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Vice President, Health Economics and Outcomes Research

Job in San Diego, San Diego County, California, 92189, USA
Listing for: Crinetics Pharmaceuticals, Inc.
Full Time position
Listed on 2026-01-11
Job specializations:
  • Management
    Data Science Manager
  • IT/Tech
    Data Science Manager
Job Description & How to Apply Below
Vice President, Health Economics and Outcomes Research page is loaded## Vice President, Health Economics and Outcomes Researchremote type:
Remote locations:
Remote time type:
Full time posted on:
Posted 4 Days Agojob requisition :
JR000539

Crinetics is a pharmaceutical company based in San Diego, California, developing much-needed therapies for people with endocrine diseases and endocrine-related tumors. We were founded by a dedicated team of scientists with the simple belief that better therapies developed from rigorous innovation can lead to better lives. Our work continues to make a real difference in the lives of patients. We have a prolific discovery engine and a robust preclinical and clinical development pipeline.

We are driven by science with a patient-centric and team-oriented culture. Crinetics is known for its inclusive workplace culture. We are also a dog-friendly workplace. This is an exciting time to join Crinetics as we shape our organization into the world’s premier fully-integrated endocrine company from discovery to patients. Join our team as we transform the lives of others.
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* Position Summary:

** The Vice President of Health Economics and Outcomes Research (HEOR) and Real World Evidence (RWE) will serve as a strategic leader, advancing Crinetics’ mission to improve the lives of patients with rare endocrine diseases. Reporting to the Senior Vice President of Medical Affairs, this role will define and execute a global HEOR and RWE strategy that integrates advanced analytics, digital health, and patient-centric evidence approaches across the product lifecycle.

The VP will drive U.S. market access priorities while shaping global evidence frameworks to support optimal reimbursement and value recognition.

The VP will oversee the design and delivery of high-impact real-world studies and health economic models, leveraging multi-source data to demonstrate the clinical, humanistic, and economic value of Crinetics’ portfolio, including therapies for Acromegaly, Cushing’s disease, Congenital Adrenal Hyperplasia, and other endocrine disorders. In addition to leading the HEOR and RWE function, the VP will partner with internal stakeholders and external experts to align evidence generation with clinical development, commercialization, and payer engagement strategies worldwide.
** Essential Job Functions and Responsibilities:
** These may include but are not limited to:
** Strategic Leadership
*** Develop, lead, and operationalize a global HEOR and RWE strategy, embedding advanced real-world data science, digital health, and AI-driven analytics across the product lifecycle to accelerate evidence generation and value demonstration.
* Serve as the organization’s primary subject matter expert, principal thought leader, and spokesperson on HEOR and RWE, including payer evidence needs, health outcomes trends, and value demonstration strategies.
* Set the enterprise-wide vision for RWE, including multi-country, multi-source data acquisition strategies including data from insurance claims, electronic health records, patient registries, digital devices, patient apps, and social determinants of health.
* Oversee external non-employee resources, vendors, and partners to ensure timely, high-quality deliverables aligned with strategic priorities.
** Team Leadership & Organizational Development
*** Build and mentor a high-performing global RWE and HEOR leadership team, fostering a collaborative, mission-driven culture.
* Manage external research partners, consultants, CROs, and data vendors to ensure delivery of innovative, high-quality work.
* Lead enterprise-wide training programs on RWE best practices, digital health, and advanced analytics for internal and external stakeholders.
** Evidence Generation & Data Strategy
*** Lead the design and execution of HEOR and RWE across U.S. and global markets, ensuring alignment with regulatory, payer, and clinical priorities. This includes:  + Observational and non-interventional studies leveraging diverse real-world data sources.  + Integrated analyses of insurance claims and electronic health record (EHR), and patient registries.  + Advanced economic modeling and linked data…
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