Principal Cloud & Infrastructure Engineer | Temporary & Onsite

Overview

Who We Are:

Neurocrine Biosciences is committed to a strong, inclusive culture based on our shared purpose and values. We strive to relieve suffering for people with great needs and to support our people as we pursue brave science.

What We Do:

Neurocrine Biosciences is a neuroscience-focused biopharmaceutical company dedicated to discovering and developing life-changing treatments for under-addressed neurological, neuroendocrine, and neuropsychiatric disorders. Our portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal hyperplasia, endometriosis, and uterine fibroids, with a robust pipeline in mid- to late-stage development. For more information, visit  and follow us on Linked In, X, and Facebook.

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* in collaboration with Abb Vie)

The Principal Cloud and Infrastructure Engineer serves as the senior technical authority responsible for designing, modernizing, and optimizing enterprise-scale Azure-centric cloud environments integrated with AWS and on-premises infrastructure. This role drives large-scale platform transformations including workload migration, infrastructure consolidation, automation-first provisioning, cost optimization, GxP-aware cloud environments, and performance engineering across hybrid architectures. The position requires deep expertise in Azure cloud engineering, strong AWS experience, and hands-on integration with VMware virtualization, enterprise storage, identity systems (AD/Azure AD), networking, and scientific compute platforms.

The Principal Engineer defines platform strategy, establishes architectural standards, leads complex cross-functional programs, and ensures secure, compliant, highly available, and cost-efficient operations across the enterprise.

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• Lead large-scale technology infrastructure consolidation, virtualization, and cloud migration initiatives.

• Drive automation-first engineering using Infrastructure as Code (Terraform, ARM/Bicep, Cloud Formation) across cloud and on-prem environments.

• Design and implement API-driven, self-service provisioning platforms integrated with Service Now and identity systems.

• Lead cloud cost optimization and Fin Ops initiatives across Azure and AWS, including savings strategies and governance controls.

• Architect and optimize VMware platforms with high availability, disaster recovery, and footprint reduction strategies.

• Design scalable storage architectures across Azure, AWS (S3, FSx), and on-prem Net App with automated tiering and lifecycle management.

• Enable secure, on-demand compute platforms supporting containerized workloads (Docker/Kubernetes) and advanced analytics use cases.

• Implement identity-driven access models using AD/Azure AD with policy-based provisioning and role-based controls.

• Design and implement hybrid connectivity models including Express Route, VPN, SD-WAN, private endpoints, and secure access solutions.

• Integrate security, compliance, and regulatory best practices (including GxP-aware environments) into hybrid architectures.

• Build enterprise observability frameworks including performance, reliability, utilization, and cost dashboards to drive operational excellence.

• Bachelor s degree in Computer Science, Information Technology, or related field and 6+ years of infrastructure engineering experience with 4+ years focused on AWS

• Master s degree in Computer Science, Information Technology, or related field and 4+ years of experience as listed above

• High School Diploma, GED, or equivalent and 10+ years of equivalent experience, training, or certifications

• Certifications such as Azure Solutions Architect Expert, Azure Dev Ops Engineer Expert or similar

• Experience supporting GxP-regulated environments

• Experience supporting scientific computing / bioinformatics workloads

• Experience with container-based platforms (Docker, Kubernetes)

• Experience building self-service automation frameworks

• Fin Ops or cloud cost governance experience

• Azure Solutions Architect Expert (required)

• AWS Solutions Architect (preferred)

• Understands key business drivers and uses this understanding…