Principal Software QA Engineer

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At Veracyte, we offer exciting career opportunities for those interested in joining a pioneering team that is committed to transforming cancer care for patients across the globe.

Working at Veracyte enables our employees to not only make a meaningful impact on the lives of patients, but to also learn and grow within a purpose driven environment. This is what we call the Veracyte way – it’s about how we work together, guided by our values, to give clinicians the insights they need to help patients make life‑changing decisions.

• We Seek A Better Way:
  We innovate boldly, learn from our setbacks, and are resilient in our pursuit to transform cancer care
• We Make It Happen:
  We act with urgency, commit to quality, and bring fun to our hard work
• We Are Stronger Together:
  We collaborate openly, seek to understand, and celebrate our wins
• We Care Deeply:
  We embrace our differences, do the right thing, and encourage each other

We are seeking a highly experienced and collaborative Principal Software QA Engineer to lead the testing process for applications at Veracyte that directly help our company expand and develop new diagnostic solutions to improve patient outcomes and lower healthcare costs.

The Principal Software Tester is a senior, hands‑on quality leader responsible for defining, executing, and continuously improving the software testing strategy within Veracyte's regulated environment. This role ensures that all software products meet applicable quality, safety, and compliance requirements while supporting efficient delivery processes. The Principal Software Tester acts as a subject‑matter expert in verification and validation (V&V), test automation, risk‑based testing, and regulatory compliance, providing technical guidance to junior testers and collaborating closely with engineering, product, and quality functions.

• Act as key point of contact for testing and QA aspects of releases, providing testing services and coordinating with internal resources.
• Develop and execute test strategies (functional, regression, integration) and test cases, develop supporting test plans and reports.
• Demonstrate strong analytical skills coupled with the ability to find and solve the root cause of problems.
• Excellent critical thinking and troubleshooting skills.
• Serve as a liaison between internal technical teams, and third‑party software vendors where applicable.
• Manage and prioritize testing‑related projects, ensuring timely delivery within scope and with a focus on quality and long‑term sustainability.
• Identify opportunities for continuous improvement and potential automation of testing strategies and processes.
• Ensure adherence to regulatory and data integrity standards across computerized systems.
• Mentor/coach junior level test team members.

• 8+ years of experience in LIMS and/or Sales Force testing, with increasing levels of responsibility.
• Bachelor’s or Master’s degree in Life Sciences, Bioinformatics, Computer Science, or a related field.
• In‑depth understanding of laboratory science workflows, particularly in genomics, molecular biology, or clinical research environments.
• Proven experience translating technical requirements into testing strategies.
• Strong communication and interpersonal skills, with the ability to lead cross‑functional discussions.
• Demonstrated ability to manage complex projects involving multiple stakeholders, with clear timelines and outcomes.
• Solid understanding of GAMP5 risk‑based computerized systems validation methodology.
• Solid understanding of regulatory requirements, including GxP, CLIA, and data integrity frameworks.

• Familiarity with Agile software development methodologies.
• Familiarity with testing tools such as Jira and requirements tools such as Jama.

For candidates based in our San Diego office
, the salary range is $157,200 – $173,600
.
For candidates based in our South San Francisco office
, the salary range is $179,000 – $200,000
.
For candidates working remote (US), the salary range is $150,200 – $174,400
.
The final salary offered to a successful candidate will…