VP or SVP of Clinical Development

Overview

About Radionetics Radionetics Oncology, Inc. is a clinical stage company focused on the discovery and development of novel radiopharmaceuticals for the treatment of a wide range of oncology indications. Radionetics Oncology is supported by Frazier Life Sciences, 5AM Ventures, DCVC Bio, Crinetics Pharmaceuticals, and Gordon

MD Global Investments and has entered into a strategic agreement with Eli Lilly. Radionetics is advancing a pipeline of first-in-class small molecule radioligands targeting G protein coupled receptors for the treatment of a broad range of cancers, including breast cancer, lung cancer, and other indications of high unmet need.

Position Summary The VP/ Senior VP of Clinical Development is a critical leadership role working closely with the CMO on the design, execution, and interpretation of clinical trials for our novel radiopharmaceutical pipeline in oncology. This individual will serve as a medical and scientific lead for assigned programs, providing strategic and operational direction to advance our innovative therapies through first-in-human studies.

The successful candidate will be a board-certified Medical Doctor (MD) with significant experience in oncology drug development, preferably with specific expertise in radioligand therapy (RLT) or nuclear medicine. The exact title (Medical Director, VP, SVP) will be determined based on the candidate's experience, scope of responsibility, and proven track record.

• Clinical Strategy & Execution (Primary Focus)
  • Clinical Program Leadership:
    Serve as a medical lead for one or more radioligand therapy programs. Develop and drive the clinical development plan, ensuring alignment with regulatory requirements and the company’s strategic goals.
  • Trial Design:
    Work closely with the CMO on the design and preparation of clinical trial protocols (first-in-human), statistical analysis plans, and clinical study reports. This includes defining patient populations, endpoints, and appropriate dose escalation strategies.
  • Study Oversight:
    Provide ongoing medical monitoring and real-time support for clinical trials, including reviewing and interpreting clinical data, assessing safety signals, and determining the medical eligibility of subjects.
  • Data Interpretation:
    Perform clinical data review and interpretation, including the preparation of top-line results, integrated summaries of safety and efficacy, and final reports.

• Cross-Functional & Stakeholder Management
  • Regulatory Interaction:
    Serve as a medical expert in interactions with regulatory authorities globally. Prepare and present clinical data during meetings to support regulatory filings and development.
  • Collaborative Leadership:
    Work closely with cross-functional teams, including Research & Discovery, Translational Medicine, Biostatistics, Clinical Operations, Regulatory Affairs, and CMC to ensure seamless program execution, recognizing the unique supply chain and manufacturing needs of RLTs.
  • External Expertise and Communication:
    Establish and maintain relationships with key opinion leaders (KOLs), investigators and clinical site staff to garner clinical insights. Travel to sites to enhance engagement and drive clinical trial enrollment.

• Medical/Scientific Communication
  • Publications & Presentations:
    Lead the preparation of clinical trial results for publication in peer-reviewed journals and presentation at major scientific congresses (e.g., ASCO, ESMO, SNMMI).
  • Internal Communication:
    Provide internal medical and scientific training to internal teams (e.g., business development, commercial, medical affairs) as needed.

• Minimum required qualifications
  • Education:
    
    M.D. required. Board Certification/Eligibility in Oncology, Hematology/Oncology, or Nuclear Medicine is highly preferred.
  • Experience:
    
    Minimum 6-12+ years of industry clinical development experience, with a focus on oncology. Progressive leadership experience in clinical development, with demonstrated ability to define and execute global clinical strategies for complex therapeutics.
  • Oncology Expertise:
    Deep knowledge of the oncology landscape, including standard of care, translational research, and emerging therapeutic…