TEMP - Scientist, In Vivo Pharmacology; Immunology​/Neuroimmunology

Overview

Who We Are:

At Neurocrine Biosciences, we pride ourselves on a strong, inclusive, and positive culture based on our shared purpose and values. We are passionate about our people and our goal to relieve suffering for people with great needs.

Neurocrine Biosciences is a leading neuroscience-focused biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs. We are dedicated to discovering and developing life-changing treatments for patients with under-addressed neurological, neuroendocrine and neuropsychiatric disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal hyperplasia, endometriosis and uterine fibroids, as well as a robust pipeline in mid- to late-phase clinical development across core therapeutic areas.

For three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders. For more information, visit , and follow the company on Linked In, X, and Facebook. (
* in collaboration with Abb Vie)

Perform assigned experiments at Neurocrine to support in vivo and ex vivo studies to advance drug discovery. Responsibilities include rodent handling, dosing (PO, SC, IP, IV), clinical observations, and biologic sample collection, along with ex vivo assays such as flow cytometry, cytokine measurements, and basic molecular biology to interpret in vivo results. Ensures accurate record-keeping, data analysis, cross-functional participation, and compliance with SOPs and company policies.

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• Performs in vivo and ex-vivo studies to support scientific activities and project goals for immunology programs
• Performs rodent handling and procedures including dosing (PO, SC, IP, IV, RO) and clinical health assessments
• Contributes to study planning and works with cross-functional partners to align endpoints and timelines
• Collects biologic samples and tissues; performs necropsy and tissue processing to support PK/PD, biomarker, and efficacy endpoints
• Executes ex vivo cellular assays to interpret in vivo observations, including multiparametric flow cytometry and cytokine measurement assays
• Operates and maintains laboratory equipment with accurate, timely record keeping; troubleshoots and recommends process improvements
• Maintains and updates SOPs and writes data summaries/reports for experiments conducted
• Actively participates in and presents to cross-departmental teams and meetings
• Reviews, comprehends and complies with all SOPs, IACUC procedures, and safety and quality assurance standards at all times

• BS/BA degree in biological sciences preferably related to immunology, pharmacology or a related discipline and 2+ years of experience in the handling and dosing of rodents in a laboratory setting OR
• MS/MA degree in biological sciences preferably related to immunology, pharmacology or a related discipline and some relevant experience preferred OR
• Doctorate degree in biological sciences preferably related to immunology, pharmacology or a related discipline and some relevant experience preferred. Experience with ex vivo immunology assays (flow cytometry, cytokine quantification) and/or immunology disease models preferred
• Experience in executing pre-clinical in vivo studies and integrating PK with PD/efficacy
• Strong knowledge of scientific principles, methods, and techniques
• In vivo experience of autoimmune diseases and other inflammatory diseases is a plus. Also knowing how to develop animal disease models
• Strong communication, problem-solving, and analytical thinking skills
• Ability to meet multiple deadlines with a high degree of accuracy and efficiency
• Detail-oriented yet can see the broader picture of the scientific impact on the team
• Adherence to good research practices and laboratory notebook/record-keeping
• Advanced multitasking, troubleshooting, and deductive reasoning skills required
• Strong interpersonal skills and the ability to excel in a highly collaborative environment
• Willing to work some weekends and holidays as needed
• Ability to work in a fast-paced environment and adapt to change
• Other duties as assigned

Neurocrine Biosciences is an EEO/Disability/Vets employer. We are committed to building a workplace of belonging, respect, and empowerment, and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don’t line up to exactly what we have outlined in the job description.