Sr Manager, Finance; San Diego​/Hybrid

What if the work you did every day could impact the lives of people you know? Or all of humanity? At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life‑changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients.

Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world‑changing projects, you will do more and become more than you ever thought possible.

The Senior Finance Manager is the key business partner for MTT, playing a critical role in financial planning, analysis, and strategic decision‑making. This role serves as the primary Operations Finance representative, leading cross‑functional collaboration and providing financial leadership for all NPI‑related activities. It is a highly visible position supporting Operations and Finance leaders, requiring adaptability to fast‑changing conditions while delivering timely, accurate analytics and reporting.

The role partners closely with business leaders to ensure financial discipline, optimize operational performance, and drive long‑term value creation.

• This is a full‑time role, Monday through Friday, with an expectation of 2–3 in‑office days per week and additional on‑site presence as needed. The individual must reside in the San Diego area and be able to commute to our corporate offices.

• Serve as a Finance business partner for MTT, building key relationships and supporting the achievement of the departmental priorities and key objectives.
• Perform financial analysis to understand costs, benefits, and return on investment for consumables and instruments NPI and other strategic projects.
• Enable prudent decision‑making by collaborating with business SMEs across several functions in the company to evaluate the financial implications of strategic choices and build thorough business cases.
• Analyze, synthesize and translate data into key strategic inputs and insights that will drive strategic decision making at the executive level.
• Assist in the preparation of economic analysis to support new operating decisions and investment opportunities including cost‑savings initiatives, in sourcing versus outsourcing decisions, and adoption of new manufacturing technologies and ensure that the appropriate financial and business risks have been identified and evaluated.
• Track actual costs and milestone dates for our projects, analyze anticipated manufacturing costs for new products and assist with analyzing trade‑off decisions in the development process.
• Assist the operating groups in preparing forecasts and budgets and identifying the underlying reasons for variances from those financial plans including monitoring adherence to the approved budget.
• Manage financial close and forecast activities. Tracking, reporting, and sharing financial performance on OpEx and Cap Ex with business partners and finance leadership on a timely manner.
• Work with business SMEs to monitor ongoing Operations costs and help identify opportunities for improving margins.
• Maximize long‑term shareholder value while protecting corporate assets.

Listed responsibilities are an essential, but not exhaustive list, of the usual duties associated with the position. Changes to individual responsibilities may occur due to business needs.

• Typically requires a Bachelor’s degree in Finance, Accounting, Business Administration, or related field, and a minimum of 12 years of progressively responsible Finance experience, including 3–6 years of Management experience.
• Strong knowledge of cost accounting, inventory management, variance analysis, gross margin analysis, and budgeting and forecasting.
• Solid understanding of US GAAP; familiarity with SEC reporting requirements is a plus.
• Advanced proficiency in financial modeling and analysis.
• Advanced Excel and PowerPoint skills required.
• Experience with SAP and financial planning/reporting tools (e.g., TM1,…