Chief Medical Officer

Company Overview

Two Step Therapeutics is a biotechnology company developing a pipeline built around a unique tumor-targeting polyspecific integrin-binding peptide (PIP) that can selectively bind several targets highly expressed on solid tumors. This multi-targeting feature enables the agent’s broad applicability to a wide range of tumor types and patient populations, overcoming the limitations of single-antigen targeting approaches. The company has leveraged this technology to create a pipeline of targeted cancer therapies for cytotoxic drug delivery and radioligand therapy.

Two Step Therapeutics was co-founded by CEO, Caitlyn Miller, in collaboration with leading academic entrepreneurs at Stanford University, including Nobel Laureate Carolyn Bertozzi, Jennifer Cochran, and Ronald Levy.

For more information, visit  or download our 2025 scientific poster (linked here).

We are seeking a Chief Medical Officer (CMO) to oversee and advance a differentiated pipeline of targeted drug conjugates and radioligand therapies designed to address high unmet needs across multiple solid tumor indications. The ideal candidate is a proven cross-functional development leader with experience advancing targeted oncology modalities (e.g., ADCs, peptide-drug conjugates, radioligands) from IND-enabling through late-stage clinical development.

• Lead the overarching clinical development strategy and execution for the pipeline, ensuring seamless alignment with corporate goals, scientific innovation, and long-term patient impact.
• Serve as the primary medical expert for novel therapeutics to deliver rigorous, high-quality clinical, scientific, and regulatory outcomes.
• Collaborate closely with R&D, and external partners to align clinical strategies with corporate priorities, manufacturing capabilities, and development plans.
• Lead the preparation, review, and submission of critical regulatory documents (e.g., protocols, Investigator's Brochures) to enable efficient early-phase clinical development.
• Cultivate and maintain relationships with Key Opinion Leaders (KOLs), academic investigators, advisory boards, CROs, and trial sites.
• Engage effectively with investors, board members, and external stakeholders to communicate program progress, scientific rationale, and strategic value.

• Education:

  MD with board certification in a relevant specialty (e.g., oncology, nuclear medicine, radiation oncology, or related therapeutic area).

• 15+ years of progressive clinical leadership experience in the biotech or pharmaceutical industry, with a demonstrated track record of successfully advancing novel therapeutics from preclinical/early clinical stages through pivotal development.
• Proven expertise in global regulatory interactions, including successful submissions, negotiations, and approvals with major agencies (FDA, EMA, and others) across early and late-stage programs.
• Prior experience in a CMO, senior VP of Clinical Development, or equivalent medical leadership role in a biotech or pharmaceutical organization, ideally in a fast-paced, innovative environment.
• Hands-on, execution-oriented mindset with a willingness to actively contribute to pipeline advancement, including protocol design, data interpretation, and cross-functional problem-solving.
• Exceptional scientific judgment, strategic thinking, and communication skills

• Expertise with drug conjugates (i.e., peptide-drug conjugates, ADCs) and/or radioligand programs

At Two Step Therapeutics, we envision a future where every cancer patient has access to targeted, safe, and effective therapeutic options. We prioritize a diverse, inclusive work environment that fosters personal and professional growth. Our comprehensive benefits include:

• Competitive base salary, performance bonuses, and equity compensation
• Unlimited Paid Time Off (PTO)
• Comprehensive medical, dental, and vision benefits for individuals and families
• 401(k) plan
• Company-paid basic life insurance

Two Step Therapeutics is an equal opportunity employer. We prohibit unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, mental/physical disability, medical condition, marital status, veteran status, or any other characteristic protected by law. If you require assistance in submitting an application due to incompatible assistive technology or a disability, please contact us at  We are committed to accommodating your needs promptly.

If you are passionate about advancing cancer therapies and want to make a meaningful impact in the field, we invite you to apply for the Chief Medical Officer position at Two Step Therapeutics. Together, we can shape the future of cancer treatment.