Research Associate, Research Scientist, Clinical Research

Priority Review Date (Note - Posting may close at any time)

The Jurynec Lab (Department of Orthopaedics,(Use the "Apply for this Job" box below).) is looking for a highly motivated and independent Post Doctoral Research Fellow to be part of a multidisciplinary team studying the genetics of osteoarthritis. The lab uses human genetics, bioinformatics, molecular biology, and animal models to understand the factors that contribute to the onset and progression of osteoarthritis.
The Jurynec Lab has identified over 100 candidate gene variants that segregate with osteoarthritis in large pedigrees. We are analyzing candidate gene functions in tissue culture and generating mice that harbor human disease alleles to understand the contribution of these genes to the osteoarthritis phenotype. Analyses include CRISPR /Cas9 genome editing in mouse, scRNA-seq, spatial profiling, WES / WGS , and tissue culture.

The candidate should be prepared to analyze gene function in vivo and perform genetic and chemical screens in vitro to identify potential therapeutics. The lab is funded by the NIH and foundation grants.
The applicant will be responsible for leading independent projects under the guidance of the PI. These studies include performing experiments with zebrafish, mice, and tissue culture. The applicant will also be responsible for the maintenance and breeding of zebrafish and mice.

• 1. Performs and directs specialized and complex lab tests, experiments and surgical procedures for studies.
• 2. Assists the Principal Investigator in the design, implementation and performance of new protocols and procedures as well as the modification of existing techniques.
• 3. Reviews scientific journals, abstracts and other literature for information concerning experimental procedures.
• 4. Makes advanced statistical calculations, analyzes data and prepares reports summarizing research results.
• 5. Operates complex and highly specialized laboratory and surgical instruments and equipment. Instructs others in their use.
• 6. Maintains a log of supplies used in procedures.
• 7. May supervise, train and review the work of laboratory personnel.
• 8. May prepare equipment and rooms for studies.
• 9. May assist with preparing budgets.

The Post Doc assists in the development of research protocols and designs. Modifies and implement procedures. Records and interprets research results. The incumbent works independently, under the general supervision of most senior laboratory personnel. Work may include training and supervising other laboratory personnel, who may refer sensitive or unusual situations to the incumbent. Problems that cannot be resolved by the incumbent will be referred to the most senior Lab personnel.

PhD or BS with 5+ years of experience for qualifications>

Nearly Continuously:
Laboratory environment.
Often:
Exposure to animals, hazards (includes a variety of physical conditions, such as proximity to moving mechanical parts, moving vehicles, electrical current, working on scaffolding and high places, or exposure to chemicals).
Seldom:

Nearly Continuously:
Hearing, listening, talking.
Often:
Repetitive hand motion (such as typing), walking, standing, sitting.
Seldom:
Bending, reaching overhead.

The University is a participating employer with Utah Retirement Systems (“URS”). Eligible new hires with prior URS service may elect to enroll in URS if they make the election before they become eligible for retirement (usually the first day of work). Contact Human Resources at  for information. Individuals who previously retired and are receiving monthly retirement benefits from URS are subject to URS’ post-retirement rules and restrictions.

Please contact Utah Retirement Systems at  or  or University Human Resource Management at  if you have questions regarding the post-retirement rules.
This position may require the successful completion of a criminal background check and/or drug screen.
The University of Utah values candidates who have experience working in settings with students and patients from all…