Senior Scientist; Computational - Genetics

Position: Senior Scientist (Computational) - Genetics
Location: St. Louis

* Collaborates on designing, conducting and reporting of research projects.
* Leads the process of monthly cleaning of servers and network attached storage across a 25 person laboratory to facilitate major long-term cost savings for the lab.
* Oversees the code development and data storage and accessibility needs of the laboratory toward discovery-based science across all genomics, imaging, and connectome data. Develops key algorithm in collaboration with other graduate students, postdocs, and scientists in the laboratory to advance the laboratories papers and discoveries.
* Trains to achieve mastery and excellence in code to call compartments, TADs, subTADs, loops in Hi-C/Micro-C/snm3c  data, as well as in peak calling of Chip-seq, Cut&Run and Cut&Tag data. Establishes mastery codes in analyzing DNA damage repair, genomic instability data. Oversees trainees to ensure code and parameter selection implemented at highest standards.
* Creates algorithms to analyze data generated by their projects to create paper figures and make discoveries.
* Guides lab members to write and edit methods sections and figures for research papers where the analysis is used in the manuscript.
* Oversees junior computational scientists to ensure data is organized, managed, and curated on the cluster and servers to find biological patterns in a wide range of genetic and epigenetic sequencing and imaging data to facilitate the paper figures of lab members.
* Assists with grant preparation and reporting (editing, formatting, and facilitating stylistic and grammatical edits for lab’s annual grant progress reports, coordinating team members to arrange scientific content to meet grant progress deadline).
* Prepares and submits papers on research.
* Assists PI in filling out of paperwork, including, but not limited to: dbGAP and ENCODE data portal approvals, Grant and University-related paperwork, yearly RRPR reports for every one of the lab’s grants - including coordinating with the subTeam members to get the content assembled.
* Oversees and writes established SOPs for data storage and movement onto GEO and NIH portals for public data accessibility.
* Trains new lab members on algorithms, bitbucket/github, data naming conventions, and GEO.
* Manages research project with other institutions and investigators.
* Performs other duties as assigned.
* Familiar with genomics assays and their computational pipelines, image processing (segmentation, spot calling, drift correction).
* Exceptional commitment to upholding the collaborative ethos of the Cremins laboratory.
* Strong skills in verbal and written communication with a dedication to open transparent communication with mentors and peers.
* Strong orientation to detail with exceptional organizational skills.

Demonstrated ability to handle daily laboratory challenges with a dedication to the values of reconciliation, unity, mutual honor, and respect.
* Up to 22 days of vacation, 10 recognized holidays, and sick time.
* Competitive health insurance packages with priority appointments and lower copays/coinsurance.
* Take advantage of our free Metro transit U-Pass for eligible employees.
* WashU provides eligible employees with a defined contribution (403(b)) Retirement Savings Plan, which combines employee contributions and university contributions starting at 7%.
* WashU covers the cost of tuition for you and your family, including dependent undergraduate-level college tuition up to 100% at WashU and 40% elsewhere after seven years with us.

Washington University in St. Louis' collective success is significantly attributed to the passion and outstanding efforts of our community. Our staff, faculty and trainees are committed to excellence and dedicated to carrying out our missions of research, teaching and patient care.

WashU prides itself on being a place where people matter, and serious work is done. Our people work together in an inclusive community that celebrates diverse perspectives, collaboration and innovation. We are a community of individuals inspired to work together to develop big ideas and tackle challenging problems.

We value the well-being of our people. WashU strives to create a positive employee experience where staff, faculty and trainees thrive, both personally and professionally. Our employees find meaning, connection and vitality in their work and life with a healthy work-life balance and support to learn, grow and make an impact at WashU, the community and the world.
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